January 2011

Theoretical analysis indicating that human genome is not a blueprint and that human oocytes have the instructions

Is human genome really a blueprint? If it is not a blueprint, how are human bodies constructed? This paper solves this hypothetical proposition. Firstly, it indicates 8 examples of important biological pathways and factors among house-keeping genes and proved that human genome is not a blueprint, but a storage of genes. Secondly, it proved that human oocytes have the instructions for development and differentiation. In...

Author(s): Koichi Itoh

January 2011

An insight into blood clotting disorders in humans

The structure of thrombin protein Oncorhynchus mykiss had not yet been resolved by NMR or X-ray diffraction method. In the present work, we have modeled the structure of protein using Modeller 9v1, taking human thrombin protein as the template. Furthermore, the antithrombin protein was docked with the best model generated by R-dock and Z-dock module of INSIGHT II and the nine potential amino acids involved in...

Author(s): Parul Johri, Sagar Nagare, Kakumani Venkateswara Swamy and Chitta Suresh Kumar