February 2010

Alteration in chemical composition of red blood cells in iron deficiency anemia

The alteration in the chemical composition of plasma in health and diseases is well studied, but the changes in interior milieu of erythrocytes are not properly explored. We have studied 15 parameters (carbohydrates, lipids, proteins, electrolytes / cations, anions, metabolites, iron compounds etc.). All the studied parameters were significantly decreased in iron deficient anemic erythrocytes, except...

Author(s): Neelima Hemkar, D. C. Sharma and Manminder Riyat

February 2010

Influence of cimetidine and bromocriptine on weight of rats and its relation with fertility

The present study was designed to see the influence of parenterally administered drugs cimetidine and bromocriptine on the weight of adult male albino rats and its relation with fertility. Ninety adult young male albino rats between the ages of 60 to 120 days were selected. The animals were divided into three groups. Cimetidine was administered in a dose of 200 mg/kg body weight to group B intramuscularly and in...

Author(s): Qamar Hamid, Liaqat Ali Minhas, Sadaf Hamid and Anjuman Gul

February 2010

Role of GSTM1 gene polymorphism and its association with coronary artery disease

Coronary artery disease (CAD) is one of the leading causes of mortality and morbidity worldwide. Complex interplay of environmental and genetic factors has been known to contribute to CAD pathophysiology. Variations in several genes have been found to be associated with risk for developing CAD in different populations. Glutathione S-transferases (GSTs) play a primer role in cellular defense against electrophilic...

Author(s): Rabbani Syed, , Farha Deeba and Kaiser Jamil,