Journal of
Diabetes and Endocrinology

  • Abbreviation: J. Diabetes Endocrinol.
  • Language: English
  • ISSN: 2141-2685
  • DOI: 10.5897/JDE
  • Start Year: 2010
  • Published Articles: 65

Full Length Research Paper

Antidiabetic properties of Moringa oleifera: A review of the literature

Fatoumata BA.
  • Fatoumata BA.
  • Health Sciences Unit, Laboratory of Physiology and Functional Explorations, University Gaston Berger, Senegal.
  • Google Scholar
MamadouSaïdou BAH.
  • MamadouSaïdou BAH.
  • Health Sciences Unit, Laboratory of Physiology and Functional Explorations, University Gaston Berger, Senegal.
  • Google Scholar
Mohamet SENE
  • Mohamet SENE
  • Health Sciences Unit, Laboratory of Physiology and Functional Explorations, University Gaston Berger, Senegal.
  • Google Scholar
Joseph Koulanzo SAMBOU
  • Joseph Koulanzo SAMBOU
  • Health Sciences Unit, Laboratory of Physiology and Functional Explorations, University Gaston Berger, Senegal.
  • Google Scholar
Modou Mbacké GUEYE
  • Modou Mbacké GUEYE
  • Health Sciences Unit, Laboratory of Physiology and Functional Explorations, University Gaston Berger, Senegal.
  • Google Scholar
El HadjiMakhtar BA
  • El HadjiMakhtar BA
  • Department of Neurosciences, Faculty of Medecine and Pharmacy, University Cheikh Anta Diop, Senegal.
  • Google Scholar


  •  Received: 22 December 2019
  •  Accepted: 15 April 2020
  •  Published: 30 April 2020

References

Abdulkadir AR, Zawawi DD, Jahan MS (2016).Proximate and phytochemical screening of different parts of Moringa oleifera. Russian agricultural sciences 42(1): 34-36.
Crossref

 

Adeeyo AO, Adefule AK, Ofusori DA, Aderinola AA, Caxton-Martins EA (2013). Antihyperglycemic effects of aqueous leaf extracts of mistletoe and Moringa oleifera in streptozotocin-induced diabetes Wistar rats. DiabetologiaCroatica 42(3):1-8.

 

Agoyi EE, Assogbadjo AE, Gouwakinnou GN, Okou FAY, Sinsin B (2014). Ethnobotanical Assessment of Moringa oleifera Lam in Southern Benin (West Africa). Ethnobotany Research and Applications 12:551-560.
Crossref

 

Aja PM, Nwafor EJ, Ibiam AU, Orji OU, Ezeani N, Nwali BU (2013). Evaluation of anti-diabetic and liver enzymes activity of aqueous extracts of Moringa oleifera and Brideliaferruginea leaves in alloxan induced diabetic Albino rats. International Journal of Biochemistry Research & Review 3(3): 248-258.
Crossref

 

Altom HAB, Bjadalla JB, Tibin MAM, Eshag NA, Bukhari SA, Salih EM (2018).Feeding Moringa oleifera meal to Sudanese desert goats and its impacts on milk yield and composition in North Kordofan, Sudan. Sudan Journal of Science and Technology 19(1):8-18.

 

Atakpama W, Kponor E, Kanda M, Dourma M, M'tékounmNare, Batawila K, Akpagana K (2014).Moringa oleifera Lamarck (Moringaceae): uneressourcephytogénétique à usage multiple. Revue CAMES, Sciences de la vie, de la terreetagronomie 2(1):6-14.

 

Ayeni MJ, Joshua K, Oscar CU (2016). Ethno-Medicinal Survey of Leafy Vegetables Among Igbo and Hausa Tribes Residents in Ado-Ekiti, Nigeria. Journal of Botanical Papers 1:8-14.

 

Bhattacharya A, Tiwari P, Kumar S (2018). A review of the phytochemical and pharmacological characteristics of Moringa oleifera.Journal of Pharmacy And Bioallied Sciences 10(4):181-191.
Crossref

 

Belhi M, Selmi H, Abbes C, Tibaoui SJG, Rouissi H (2018). The antioxidant activity and the ruminal fermentation parameters of Moringa oleifera L. among sheep and goats. Journal of Agriculture and Environmental Sciences 7(1):83-92.
Crossref

 

Bundi LK, Njeru CW (2018). Use of vegetative wastewater treatment systems for counties' effluent management in Kenya. Rwanda Journal of Engineering, Science, Technology and Environment 1(1):1-7.
Crossref

 

Cáceres A, Saravia A, Rizzo S, Zabala L, De Leon E, Nave F (1992). Pharmacologie properties of Moringa oleifera.Screening for antispasmodic, antiinflammatory and diuretic activity. Journal of Ethnopharmacology 36(3):233-237.
Crossref

 

Delattre J, Gardès M, Jore D (2001). Stress oxydantetdiabètesucré. Journal de la Société de Biologie 195(4):375-376.
Crossref

 

Diop E (2014). Contribution à l'étude de la pharmacopéetraditionnelle: enquêteethnopharmacologiquedans le département de Nioro du RIP. Thèse de doctoratpharmacie. UCAD, Dakar, 32: 89.

 

Diop RD, Mbaye MS, Diop I, Bassène C, Sarr O, Camara AA, Sy MTA, Noba K (2019). Usages médicinales des plantes par la population riveraine du conservatoire botanique Michel Adanson de Mbour (Sénégal). Journal of Animal & Plant Sciences 40(3): 6690-6711.
Crossref

 

Dongock DN, Bonyo AL, Mapongmestem PM, Bayegone E (2018). Etude ethnobotaniqueetphytochimique des plantesmédicinalesutiliséesdans le traitement des maladies cardiovasculaires à Moundou (Tchad). International Journal of Biological and Chemical Sciences 12(1): 203-216.
Crossref

 

Etuk EU, Mohammed JAK (2009). Informant consensus selection method: A reliability assessment on medicinal plants used in north western Nigeria for the treatment of diabetes mellitus. African Journal of Pharmacy and Pharmacology 3(10): 496-500.

 

Edoga CO, Njoku OO, Amadi EN, Okeke JJ (2013). Blood sugar lowering effect of Moringa oleifera Lam in albino rats. International Journal of Science & Technology 3(1):88-90.

 

Fall A (2009). Etude de l'activitéanalgésique des feuillesde Moringa oleifera Lam. (Moringaceae). Thèse de doctoratpharmacie. UCAD, Dakar, 89: 84.

 

Fortin D, Lô M, Maynart G (2009). Plantesmédicinales du sahel. Dakar, Sénégal: Enda-Editions, p.278.

 

Giridhari VVA, Malathi S, Geetha K (2011). Antidiabetic property of drumstick (Moringa oleifera) leaf tablets. Journal of Health and Nutrition 2(1):1-5.

 

Gopalakrishnan L, Doriya K, Kumar DS (2016).Moringa oleifera: A review on nutritive importance and its medicinal application. Food Science and Human Wellness 5(2):49-56.
Crossref

 

Gueye M (2011). Plantesmédicinales: résultats de recherche. Dakar: Enda tiers monde. ISBN: 92 9130 084 8, 423 pages.

 

Guèye A (2016). Vente des plantesmédicinales à Touba :enquêtedans les marchés. Thèse de doctoratpharmacie. UCAD, Dakar, 93: 103.

 

Hafiz IM, Mohd ZA, Nurzalina AKK (2016). A review of promising phytochemical, nutritional and glycemic control studies on Moringa oleifera lam in tropical and sub-tropical regions. Asian Pacific Journal of Tropical Biomedicine (10):896-902.
Crossref

 

Hêdji CC, Gangbazo DK, Houinato MR, Fiogbé ED (2014). Valorisation de Azollaspp, Moringa oleifera, son de riz, et de co-produits de volaille et de poisson en alimentation animale: synthèsebibliographique. Journal of Applied Biosciences 81(1):7277-7289.
Crossref

 

Holaly GE, Simplice, KD, Charlemagne G, Kodjovi A, Kokou A, Tchadjobo T, Jacques S (2018). Étudeethnobotanique des plantesutiliséesdans le traitement du diabètedans la médecine\

 

traditionnelle de la région Maritime du Togo. The Pan African MedicalJournal 30 :186.

 

International Diabetes Federation (2017). Data from: IFD Diabetes Altas Globally, 8th Edn. Available online at: http://www.diabetesatlas.org

 

Isingoma BE, Samuel M, Edward K (2018). Determination of the minimum inhibition concentration of Moringa oleifera leaf powder against some common diarrhoea causing pathogens. Journal of Food and Nutrition Research 6(6):365-369.
Crossref

 

Jazy MA, Karim S, Morou B, Sanogo R, Mahamane S (2017). EnquêteEthnobotaniqueAuprès Des Tradipraticiens de Santé des Régions de Niamey EtTillabéri Au Niger: Données 2012-2017. European Scientific Journal 13(33):276-304.
Crossref

 

Joy AE, Kunhikatta SB, Manikkoth S (2013). Anti-convulsant activity of ethanolic extract of Moringaconcanensis leaves in Swiss albino mice. Archives of Medicine and Health sciences 1(1):6-9.
Crossref

 

Kerharo PJ (1969). UnremèdepopulaireSénégalais: Le 'Nebeday' (Moringa oleifera lam.) emploisthérapeutiques en milieu Africainchimie et pharmacologie. PlantesMédicinaleset Phytothérapie 3:14-219.

 

Khan W, Parveen R, Chester K, Parveen S, Ahmad S (2017). Hypoglycemic potential of aqueous extract of Moringa oleifera leaf and in vivo GC-MS Metabolomics. Front. Pharmacol 8:577.
Crossref

 

Khawaja TM, Tahira M, Ikram UH (2010).Moringa oleifera: a natural gift-A review. Journal of Pharmaceutical Sciences & Research 2(11):775-781.

 

Kofia M, Esther N, Ndoe MG et al (2017). Biological Investigation of the Benefits and Risk of Plants Consumed by Diabetics in Ngaoundere. Cardiology and cardiovascular research 1(3):57-61.

 

Koné JP (2017). Etude de 5 plantesutilisées par les tradipraticiens de santé Bwa de la commune 1 du district de Bamako pour le traitement

 

traditionnelle du diabète. Thèse de doctoratpharmacie. USTTB, Bamako, p.121.

 

Konmy BBS, Okounlade PA, Allou SYD, Azando EVB, Hounzangbe-Adote MS (2016). A review on phytochemistry and pharmacology of Moringa oleifera leaves (Moringaceae). Journal of pharmacognosy and phytochemistry 5(5):325-330.

 

Kouakou AYF, Kamagate A (2016). Contribution de la MédecineTraditionnelleIvoiriennedans le Traitement de l'Obésitéet du Diabète/Contribution of Ivorian Traditional Medicine in the Treatment of Obesity and Diabetes. International Journal of Innovation and Applied Studies 18(4):1159-1166.

 

Laleye FOA, Mensah S, Assogbadjo AE, Ahissou H (2015). Diversity, knowledge, and use of plants in traditional treatment of diabetes in the Republic of Benin.Ethnobotany Research and Applications 14:231-257.
Crossref

 

Luka CD, Tijjani H, Joel EB, Ezejiofor UL, Onwukike P (2013). Hypoglycaemic properties of aqueous extracts of Anacardiumoccidentale, Moringa oleifera, Vernoniaamygdalina and Helianthus annuus: a comparative study on some biochemical parameters in diabetic rats. Inter J Pharm Sci Invent 2(71):16-22.

 

Lunyera J, Wang D, Maro V, Karia F, Boyd D, Omolo J, Stanifer JW (2016). Traditional medicine practices among community members with diabetes mellitus in Northern Tanzania: an ethnomedical survey. BMC complementary and alternative medicine 16(1):282.
Crossref

 

Mawouma S, Mbofung CM (2014). Usages alimentaires de Moringa oleiferadans la région de l'Extrême-Nord Cameroun. International Journal of Biological and Chemical Sciences 8(4):1847-1852.
Crossref

 

Mballo M (2010). Inventairetaxonomiqueet importance médicinale des plantes des secteurs 13 à 16 du conservatoire botanique Michel Adanson de Mbour. Mémoired'ingénieur. ISFAR, Thiès, p.82.

 

Menasria L, Blaney S, Main B, Vong L, Hun V, Raminashvili D, Leblanc C (2018). Mitigated Impact of Provision of Local Foods Combined with Nutrition Education and Counseling on Young Child Nutritional Status in Cambodia. Nutrients 10(10):1450.
Crossref

 

Mirhashemi MS, Mohseni S, Hasanzadeh M, Pishvaee MS (2018).Moringa oleifera biomass-to-biodiesel supply chain design: An opportunity to combat desertification in Iran. Journal of Cleaner Production 203:313-327.
Crossref

 

Nadembega P, Boussim IJ, Nikiema JB, Poli F, Antognoni F (2011). Medicinal plants in baskoure, kourittenga province, Burkina Faso: an ethnobotanical study. Journal of Ethnopharmacology 133(2): 378-395.
Crossref

 

Ndiaye M, Dieye AM, Mariko F, Tall A, Sall AD, Faye B (2002). Contribution to the study of the anti-inflammatory activity of Moringa oleifera (Moringaceae). Dakar medical 47(2):210-212.

 

Ndong M, Wade S, Dossou N, Diagne R (2003). Valeurnutritionnelle du Moringa oleifera, étude de la biodisponibilité du fer, effet de l'enrichissement de divers plats traditionnelssénégalais avec la poudre des feuilles. Developing African leafy vegetables for improved nutrition 7:3-4.

 

Olayaki LA, Irekpita JE, Yakubu MT, Ojo OO (2015). Methanolic extract of Moringa oleifera leaves improves glucose tolerance, glycogen synthesis and lipid metabolism in alloxan-induced diabetic rats. Journal of basic and clinical physiology and pharmacology 26(6):585-593.
Crossref

 

Omodanisi E, Aboua YG, Oguntibeju O (2017). Assessment of the anti-hyperglycaemic, anti-inflammatory and antioxidant activities of the methanol extract of Moringa oleifera in diabetes-induced nephrotoxic male wistar rats. Molecules 22(4):439.
Crossref

 

Onyagbodor OA, Aprioku JS (2017). Moringa oleifera leaf extract inhibits diabetogenic effect of alloxan in rats. IOSR Journal of pharmacy 7(10):7-12.

 

OrganisationMondiale de la Santé (2013). Stratégie de l'OMSpour la médecinetraditionnelle pour 2014-2023.

 

Oyedepo TA, Babarinde SO, Ajayeoba TA (2013). Evaluation of anti-hyperlipidemic effect of aqueous leaves extract of Moringa oleifera in alloxan induced diabetic rats. International Journal of Biochemistry Research & Review 3(3):162-170.
Crossref

 

Popoola JO, Olawole OO (2013). Local knowledge, use pattern and geographical distribution of Moringa oleifera Lam (Moringaceae) in Nigeria. Journal of Ethnopharmacology 150(2):682-691.
Crossref

 

Rabo Y, Lawali S, Drame AY, Mahamane A (2015). Analysestructurelle dessystèmesagroforestiers à base de Moringa oleifera Lam dans les vallées du fleuve Niger et du Goulbi de Maradi (Niger). International Journal of Biological and Chemical Sciences 9(6):2555-2565.
Crossref

 

Razingué M (2010). Etude descriptive de l'itinéraireThérapeutique de 206 patients Diabétiques de type 2 au centre de Luttecontre le diabète de Bamako. Thèse de doctoratpharmacie. USTTB, Bamako, p.97.

 

Sarr O, Diatta S, Gueye M, Ndiaye PM, Guisse A, Akpo LE (2012). Importance des ligneuxfourragersdansunsystèmeagropastoral au Sénégal (Afrique de l'ouest). Revue de MédecineVétérinaire 164(1):2-3.

 

Semenya S, Potgieter M, Erasmus L (2012). Ethnobotanical survey of medicinal plants used by Bapedi healers to treat diabetes mellitus in the Limpopo Province, South Africa. Journal of Ethnopharmacology 41(1):440-445.
Crossref

 

Sèye MB (2014). Contribution à l'étude de la pharmacopéesénégalaise :enquêteethnopharmacologiquedans le département de Tivaouane. Thèse de doctoratpharmacie. UCAD, Dakar, 04: 82.

 

Soladoye MO, Chukwuma EC, Owa FP (2012). An 'Avalanche'of plant species for the traditional cure of diabetes mellitus in South-Western Nigeria. Journal of Natural Product and Plant Resources 2(1): 60-72.

 

Sy AN, Dior Fall A, Ndiaye M, Ndiaye K, Gueye RS, Bassene E, SyGY (2018). Evaluation de l'activitéantioxydante des feuilles de Moringa oleifera Lam. (Moringaceae) du Sénégal. International Journal of Biological and Chemical Sciences, 12(4):1816-1823.
Crossref

 

Tiloke C, Anand K, Gengan RM, Chuturgoon AA (2018). Moringa oleifera and their phytonanoparticles: potential antiproliferative agents against cancer. Biomedicine & Pharmacotherapy 108:457-466.
Crossref

 

Toury J, Giogi R, Favier JC, Savina JF (1963). Tables de composition des aliments de l'OuestAfricain. Dakar ORANA.

 

Tsabang N, Yedjou CG, Tsambang LWD, Tchinde AT, Dongfagsiteli N, Agbor GA, Tchounwou PBB, Nkongmeneck BA (2015). Treatment of diabetes and/or hypertension using medicinal plants in Cameroon. Medicinal & aromatic plants (Los Angel) S2:003.
Crossref

 

Umar SA, Mohammed Z, Nuhu A, Musa KY, Tanko Y (2018). Evaluation of Hypoglycaemic and Antioxidant Activity of Moringa oleifera Root in Normal and Alloxan-Induced Diabetic Rats.Tropical Journal of Natural Product Research 2(8):401-408.
Crossref

 

Vandi D, Nga EN, Betti JL, Loe GME, Ottou PBM, Priso RJ, Foze YN, Boumsong PCN, Dibong SD, Mpondo EM (2016). Contribution des populations des villes de Yaoundé et Douala à la connaissance des plantes à tanins et à anthocyanes. Journal of Animal and Plant Sciences 30(3): 4797-4814.

 

West African Health Organisation (WAHO) (2013).The West African pharmacopoeia. Kumasi, Ghana: KS PRINTKRAFT GH. LTD. ISBN: 978-9988-1-8014-0, p.253.

 

World Health Organization (2002).Traditional Medecines Strategy 2002-2005. WHO/EDM/TRM/2002.1: Geneva, Switzerland, 78p.

 

World Health Organization (2016). Diabetes country profiles 2016.
Crossref