Journal of
Entomology and Nematology

  • Abbreviation: J. Entomol. Nematol.
  • Language: English
  • ISSN: 2006-9855
  • DOI: 10.5897/JEN
  • Start Year: 2009
  • Published Articles: 122

Full Length Research Paper

Determination of the larvicidal activity of benzoyl thiosemicarbazone and its Ni(II) complex against Aedes aegypti and Anopheles darlingi larvae in Amazonas, Brazil

Rochelly da Silva Mesquita
  • Rochelly da Silva Mesquita
  • Coordenação de Sociedade, Ambiente e Saúde, Instituto Nacional de Pesquisas da Amazônia- INPA, Av. André Araújo, 2936, Aleixo, 69083-000, Manaus – Amazonas, Brazil.
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Wanderli Pedro Tadei
  • Wanderli Pedro Tadei
  • Coordenação de Sociedade, Ambiente e Saúde, Instituto Nacional de Pesquisas da Amazônia- INPA, Av. André Araújo, 2936, Aleixo, 69083-000, Manaus – Amazonas, Brazil.
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Ana Mena Barreto Bastos
  • Ana Mena Barreto Bastos
  • Instituto Federal de Educação, Ciência e Tecnologia do Amazonas - IFAM, Av. Sete de Setembro, 1975, Centro, 69020-120, Manaus–Amazonas, Brazil.
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  •  Received: 17 April 2018
  •  Accepted: 30 August 2018
  •  Published: 31 August 2018

Abstract

Due to the resistance of some mosquitoes to pyrethroids insecticides, new synthetic compounds are of great interest for the development of new insecticides against vectors of tropical diseases, especially in the Amazon region. Our aim was to synthesize and evaluate the larvicidal potential of benzoyl thiosemicarbazone and its Ni(II) complex against larvae of Aedes aegypti............ and Anopheles darlingi........... . The compounds were synthesized from thiosemicarbazide according to the literature, and the larvicidal potential was evaluated in triplicate at concentrations of 7 to 500 µg/mL. Benzoyl thiosemicarbazone and its Ni(II) complex showed an LC50 of 42.09 and 42.28 µg/mL, respectively, against . Ae. aegypti larvae. For .An. darlingi larvae, the LC50 values of benzoyl thiosemicarbazone (4.77 µg/mL) were lower than its Ni(II) complex (7.33 µg/mL). Benzoyl thiosemicarbazone presented satisfactory results against the larvae, and due to the insecticidal potential of this substance, the development of new chemical insecticides may be possible.

 

Key words: Benzoyl thiosemicarbazone, nickel (II), larvicidal activity; Aedes aegypti, Anopheles darlingi.