January 2012

Group B streptococcus infection and diabetes: A review

  Streptococcus agalactiae, a group B streptococcus (GBS), has been considered to be a major pathogen in neonates and pregnant women. Recently, there is accumulating concern about its significance for pathogenesis in non-pregnant adult patients. Diabetes is one of the most important underlying diseases for the development of GBS infection. This review will focus on the risk factors and clinical manifestations...

Author(s): Hidekatsu Yanai, Hidetaka Hamasaki, Naonori Tsuda, Hiroki Adachi, Reo Yoshikawa, Sumie Moriyama, Yoshinori Masui, and Shuichi Mishima

January 2012

Systematic variations in drug resistance among some enteric gram-negative bacilli isolated from humans and sewage

  This work was designed to undertake a comparative analysis of the drug resistance pattern of enteric bacteria isolated from humans and those isolated from the multifarious microbial environments of the sewage. Human and sewage isolates of enteric Gram-negative bacilli were examined for resistance to ten antibacterial agents. A total of 2400 bacterial isolates (from human n = 1404, and sewage n = 996) isolated...

Author(s): Eze Emmanuel A.

January 2012

Isolation of Lactobacillus plantarum from cow milk and screening for the presence of sugar alcohol producing gene

  Lactobacillus plantarum, was isolated from cow milk, characterized by partial 16S rRNA gene sequencing and phenotypic features and resoluted for the presence of bacteriocin and their activity against pathogenic organism. The organism showed very strong activity againstStreptococcus faecalis and strong activity against Bacillus mycoides, Klebsiella pnuemoniae,Staphylococcus...

Author(s): A. Mohan Kumar  and N. Murugalatha

January 2012

Evaluation of botanicals as biopesticides on the growth of Fusarium verticillioides causing rot diseases and fumonisin production of maize

  Partially (Pp) and completely purified (Cp) methanolic extracts of leaves of Cassia alata,Cymbopogon citratus (lemongrass), Mangifera indica (mango), Carica papaya (pawpaw),Citrus limon (lemon), fruits of Xylopia aethiopica, seeds of Aframomum melegueta (alligator pepper), Citrus aurantifolia (lime), Garcinia kola (bitter kola), Piper...

Author(s): Adejumo T. O.

January 2012

Searching for new antileishmanial lead drug candidates: Synthesis, biological and theoretical evaluations of promising thieno[2,3-b]pyridine derivatives

  Cutaneous leishmaniasis is a parasitic disease associated with high morbidity and mortality rates. This work reports the synthesis, biological and theoretical evaluations of a new antileishmanial series of 5-(4,5-dihydro-1H-imidazol-2-yl)-4-(arylamino)thieno[2,3-b]pyridine derivatives - 3 (H),  3a (m-CH3), 3b (m-OCH3), 3c (m-NO2), 3d (m-F), 3e (m-Br), 3f (p-CH3), 3g (p-OCH3), 3h (p-NO2), 3i (p-F), 3j...

Author(s): Luiz C. S. Pinheiro, Rodrigo Tonioni, Plínio C. Sathler, Helena C. Castro ,, Alice M. R. Bernardino, Uiaran O. Magalhães, Lúcio Cabral, Carlos R. Rodrigues, Júlio C. Borges, Maurício S. dos Santos, Vitor F. Ferreira, Samara N. Braga, Saulo C. Bourguignon, and Dilvani O. Santos