August 2020

Prevalence, susceptibility testing and multi drug resistance risk factors to methicillin resistant Staphylococcus aureus in nasal carriage of hospitalized patients and medical staff in selected hospitals in Cameroon

Methicillin-resistant Staphylococcus aureus (MRSA) is a major hospital acquired pathogen. In Cameroon, there is limited data on nasal carriage of MRSA and its antibiotic susceptibility testing and risk factors for multi resistance to antibiotics in hospitalized patients and medical staff . A prospective, qualitative, cross-sectional hospital-based study was carried out. Anterior nasal swabs were taken from 579...

Author(s): Leontine Kouemou Sinda, Jerome Nyhalah Dinga, Samuel Wanji and Sinata Shiro Koulla,  

August 2020

Biological control of black pod disease of cocoa (Theobroma cacao L.) with Bacillus amyloliquefaciens, Aspergillus sp. and Penicillium sp. in vitro and in the field

Phytopathogenic fungi, Phytophthora palmivora and Phytophthora megakarya continue to be a major threat to cocoa production worldwide. To counter these drawbacks, producers rely heavily on agrochemicals leading to pathogen resistance and environmental hazards. There is also increasing demand by cocoa consumers for pesticide-free seeds. Therefore, biological control through the use of natural microbial antagonists is more...

Author(s): Stephen Larbi-Koranteng, Richard Tuyee Awuah and Fredrick Kankam  

August 2020

MALDI-TOF MS identification and antifungal susceptibility of Candida strains isolated from vulvovaginal candidiasis by the AST-YS08® Card with Vitek 2® in Dakar, Senegal

The objective of this study is to determine the susceptibility profile of different Candida strains isolated from vulvovaginal candidiasis and identified by MALDI-TOF MS, using the AST-YS08 Card with Vitek 2. The AST-YS08 card with Vitek 2 was used to test the antifungal susceptibility of 38 clinical isolates of Candida recovered from vulvovaginal swabs throughout the period 2017 to 2018. The study included Candida...

Author(s): K. Diongue, M.T. Mané, M. A. Diallo, M. C. Seck, M. Ndiaye, A. S. Badiane, and D. Ndiaye,  

August 2020

The functional stability, bioactivity and safety profile of synthetic antimicrobial peptide SAAP-148

The synthetic antimicrobial peptide SAAP-148 was found to be effective against a wide range of (antimicrobial-resistant) gram-positive and gram-negative bacteria, in vitro and in a superficial skin infection model in mice, but not a surgical wound infection model in rats. In addition, the efficacy of SAAP-148 in protein-rich environments such as blood plasma and eschar extract is considerably reduced as compared to PBS....

Author(s): Gabrielle S. Dijksteel, Magda M. W. Ulrich,, Peter H. Nibbering, Robert A. Cordfunke, Jan W. Drijfhout, Esther Middelkoop, and Bouke K. H. L. Boekema  

August 2020

Antimicrobial activity of crude extract from Millettia ferruginea leaves and barks against selected bacterial pathogens and Candida albicans

The progressive increase in antimicrobial resistance was the major attribute among human pathogens that has given rise to the need to investigate other sources of therapy from various sources such as medicinal plants. The aim of this study was to assess the antibacterial activity of crude extract of leaves and bark of Millettia ferruginea against human pathogenic bacteria (Staphylococcus aureus and Shigella boydii) and...

Author(s): Mesay Bahiru, Geremew Tafesse, Nitin M. Chauhan and Ermias Assefa