Abstract

Factor XIII deficiency is a rare bleeding disorder, and spontaneous spleen rapture is not reported in cases of this disorder. We report 2 cases of spontaneous ruptured spleen in 2 young Pakistani boys who were known factor XIII deficiency who were presented at the same time within 24 h. Both cases were recovered and one was successfully treated conservatively while the other treated surgically by spleenectomy. It should also remind physicians that bleeding disorders may have unusual presentations and should keep in mind ruptured spleen in the differential diagnosis of patient with factor XIII deficiency presenting with acute abdomen. The treatment is either surgery or conservatively depending on the progress of the bleeding.

Key words: Factor XIII deficiency, ruptured spleen, bleeding diathesis.