Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

Full Length Research Paper

Antioxidant activity of Melissa officinalis leaves

Ekrem Koksal1, Ercan Bursal1,2, Emrah Dikici1, Fatih Tozoglu1 and Ilhami Gulcin3,4
1Department of Chemistry, Faculty of Sciences and Arts, Erzincan University, 24030-Erzincan-Turkey. 2Department of Chemistry, Faculty of Sciences and Arts, Mus Alparslan University, 49100-MuÅŸ-Turkey. 3Department of Chemistry, Faculty of Sciences, Ataturk University, 25100-Erzurum-Turkey. 4School of Health Services, Agri Ibrahim Cecen University, 04100-Agri-Turkey.
Email: [email protected]

  •  Accepted: 13 October 2010
  •  Published: 18 January 2011

Abstract

The purpose of this study was to evaluate antioxidant activities of water extract of Melissa officinalis (WEM) and ethanol extract of M. officinalis (EEM), comparatively. The WEM and EEM were evaluated for their radical scavenging activities by means of the DPPH and DMPD assays. WEM scavenged radicals effectively with IC50 values of 31.4 µg/mL for DPPH free radical and 60.5 µg /mL for DMPD cation radical. Similarly, EEM scavenged radicals effectively with IC50 values of 202.7 µg/mL for DPPH free radical and 120.9 µg/mL for DMPD cation radical. Also, total reducing power of WEM was found higher than EEM with both potassium ferricyanide reduction (FRAP) and cupric ions reduction capacity methods (CUPRAC). The present study showed that WEM have effective antioxidant and radical scavenging activities as compared to EEM.

 

Key words: Antioxidant activity, Melissa officinalis, reducing power, radical scavenging.

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