Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3831

Full Length Research Paper

Isolation and characterization of sulfated polysaccharide from the Sargassum pallidum (Turn.) C. Ag. and its sedative/hypnotic activity

Aimin Ji1,2*, Yufa Yao1, Ou Che1, Bingjun Wang1, Liang Sun1, Xiaodong Li1 and Feng Xu1
1Second Clinical Medical College and Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. 2Department of Pharmacy, Zhujiang Hospital, Southern Medical University, 253 Industry Avenue, Guangzhou 510282, P. R., China.
Email: [email protected]

  •  Accepted: 24 June 2011
  •  Published: 09 October 2011

Abstract

Sulfated polysaccharide from the Sargassum pallidum (Turn.) C. Ag. was isolated, purified and structurally characterized. The 13C-NMR and IR indicated a characteristic sulfated polysaccharide with 16.4% of sulfate group. The isolated polysaccharide with the molecular range of 10~48 KDa was constituted by xylose (35.92%), mannose (21.86%), arabinose (15.26%), galactose (13.49%), glucose (9.60%) and others (3.88%). The animal experiment results suggested its potential sedative and hypnotic potential activity.

 

Key words: Sargassum pallidum (Turn.) C. Ag, polysaccharide, sedative, hypnotic.

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