Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3778

Full Length Research Paper

Diterpene glycosides from Stevia rebaudiana

Venkata Sai Prakash Chaturvedula* and Indra Prakash
he Coca-Cola Company, Organic Chemistry Department, Research and Technology, One Coca-Cola Plaza, Atlanta, GA 30313, USA.
Email: [email protected]

  •  Accepted: 22 July 2011
  •  Published: 23 September 2011


A new diterpenoid glycoside, 13-[(2-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy] ent-kaur-16-en-19-oic acid-(4-O-(2-O-a-D-glucopyranosyl)-a-D-glucopyranosyl-b-D-glucopyranosyl) ester (1) was isolated from the commercial extract of the leaves of Stevia rebaudiana along with the known steviol glycosides including stevioside, rebaudiosides A-G, rubusoside and dulcoside A. The complete 1H and 13C NMR assignments of the new compound and rebaudioside G (2) were achieved by the extensive NMR (1H and 13C, COSY, 1D TOCSY, HSQC, HMBC) and MS spectral data as well as chemical studies.


Key words: 1H NMR, 13C NMR, 2D NMR, MS, diterpene glycosides, Stevia rebaudianaBertoni, chemical studies.