Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3831

Full Length Research Paper

Ultrasound-assisted solvent extraction of swainsonine from Oxytropis ochrocephala Bunge

Yan Wang, Yanchun Hu, Jianhua Wang*, Zibin Liu, Guodong Yang and Guoxia Geng
Department of internal medicine, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Shaanxi, China.
Email: [email protected]

  •  Accepted: 06 September 2010
  •  Published: 18 March 2011

Abstract

Swainsonine is an indolizidine alkaloid with anticancer and antiviral potency. Extracting from locoweeds is one of strategies to produce swainsonine currently. Here, ultrasound-assisted solvent extraction was reported to significantly promote isolation and purification of swainsonine from Oxytropis ochrocephala Bunge, a popular locoweed in northwestern China. The extracted swainsonine was identified by thin layer chromatography, melting point, gas chromatographic and mass spectrometric analysis. The straightforward and simple method described here would make swainsonine more readily available and aid in medical studies.

 

Key words: Swainsonine, ultrasound, solvent extraction, Oxytropis ochrocephala Bunge.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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