Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Antifatigue activity of water extracts of Toona sinensis Roemor leaf and exercise-related changes in lipid peroxidation in endurance exercise

Hai Feng1*, Haibin Ma2, Huiying Lin1 and Ramesh Putheti3
1China West Normal University, Nanchong, Sichuan Province, 637002, PRC, China. 2Tianjin Agricultural University, Tianjin City, 300384, PRC, China 3American Association of Pharmaceutical Scientists (AAPS), 236-203, Saint David Court, Maryland, USA.
Email: [email protected], [email protected]

  •  Accepted: 09 October 2009
  •  Published: 30 November 2009

Abstract

This study evaluated the antifatigue activity of water extracts of Toona sinensisRoemor leaf (ETL) and exercise-related changes in lipid peroxidation in swimming exercise of mice. Male Kunming mice were studied by being divided into four groups (n = 30 mice per group): low, medium, high-dose ETL treated groups and control group. Swimming endurance experiment were conducted after 21 days of ETL supplementation and the result showed that ETL was found to possess an antifatigue activity, extend the swimming time of the mice, prevent the increase in lactic acid, increasing content of liver and muscle glycogen of mice and may decrease the contribution of exercise-induced oxidative stress.

 

Key words: Antifatigue activity, water extracts of Toona sinensis leaf, lipid peroxidation, endurance exercise.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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