Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

Full Length Research Paper

Effect of sodium tanshinon IIA silate on heart function of children with myocarditis

Huang Weizhe1, Zhang Dongtao2, Zhang Ge3 and Li Tong4*
Email: [email protected]

  •  Accepted: 26 October 2011
  •  Published: 09 February 2012

Abstract

This study intends to evaluate the effects of sodium tanshinon IIA silate on cardiac function of children with myocarditis. 69 children were randomly divided into myocarditis untreatment and sodium tanshinon IIA silate treatment groups. Another 24 healthy children served as normal control. Our experimental results demonstrated that the sodium tanshinon IIA silate treatment can significantly improve heart function in children with myocarditis.

 

Key words: Sodium tanshinon IIA silate, myocarditis, children, troponin I.

Abbreviation

 HRV, Heart rate variability; LVEF, left ventricular ejection fraction; LVFS, left ventricular fraction shortening; VU-AMS, vrije universiteit ambulatory monitoring system; ECG,electrocardiogram; SDNN, standard deviations of all normal-to-normal intervals; RMSSD, root mean squares of the successive differences; CKMB, creatine kinase MB; SPSS, statistically package for social sciences; LF, low frequency; HF, high frequency; cTnI, cardiac troponin I;LVED, left ventricle end-diastolic diameter; WSC, water-soluble compounds; LDQ, lipophilic diterpenoid quinines; CK, Creatine kinase; FS, fractional shortening; EDD, end-diastolic dimension; ESD, end-systolic dimension; LVES, left ventricle end-systolic diameter.