Abstract

This study intends to evaluate the effects of sodium tanshinon IIA silate on cardiac function of children with myocarditis. 69 children were randomly divided into myocarditis untreatment and sodium tanshinon IIA silate treatment groups. Another 24 healthy children served as normal control. Our experimental results demonstrated that the sodium tanshinon IIA silate treatment can significantly improve heart function in children with myocarditis.

Key words: Sodium tanshinon IIA silate, myocarditis, children, troponin I.

Abbreviation

 HRV, Heart rate variability; LVEF, left ventricular ejection fraction; LVFS, left ventricular fraction shortening; VU-AMS, vrije universiteit ambulatory monitoring system; ECG,electrocardiogram; SDNN, standard deviations of all normal-to-normal intervals; RMSSD, root mean squares of the successive differences; CKMB, creatine kinase MB; SPSS, statistically package for social sciences; LF, low frequency; HF, high frequency; cTnI, cardiac troponin I;LVED, left ventricle end-diastolic diameter; WSC, water-soluble compounds; LDQ, lipophilic diterpenoid quinines; CK, Creatine kinase; FS, fractional shortening; EDD, end-diastolic dimension; ESD, end-systolic dimension; LVES, left ventricle end-systolic diameter.