Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3843

Full Length Research Paper

Alkaloid constitution of Nerium oleander using gas chromatography-mass spectroscopy (GC-MS)

Imad Hadi Hameed*
  • Imad Hadi Hameed*
  • Department of Molecular Biology, Babylon University, Hilla City, Iraq.
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Huda Jasim
  • Huda Jasim
  • Department of Molecular Biology, Babylon University, Hilla City, Iraq.
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Muhanned Abdulhasan Kareem2
  • Muhanned Abdulhasan Kareem2
  • Babylon University, Centre of Environmental Research, Babylon University, Iraq.
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Ameera Omran Hussein
  • Ameera Omran Hussein
  • Department of Molecular Biology, Babylon University, Hilla City, Iraq.
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  •  Received: 27 January 2015
  •  Accepted: 10 February 2015
  •  Published: 03 March 2015

Abstract

Oleander is an evergreen shrub or small tree from 5 to 25-ft tall containing gummy sticky sap in the dogbane family Apocynaceae. In this study, the alkaloid compounds of Nerium oleander (NO) have been evaluated. The chemical compositions of the leaf ethanol extract of N. oleander were investigated using gas chromatography-mass specroscopy (GC-MS). GC-MS analysis of N. oleander alkaloid leaf ethanol extract revealed the existence of the 5-hydrooxy methylfurfural, β-d-allopyranoside, methyle 6-dioxy-2-o methyl, cycloheptasiloxane, tetradecamethyle, cyclooctasiloxane, hexadecamethyl,  cyclononasiloxane, octadecamethyl, cyclodecasiloxane, eicosamethyl, 2-cyclopenten-1-one, 2-hydroxy-3-methyl, 9.12.15-octadecatrienoic acid, 2,3bis[trimethylsilyl]oxy] propyl ester, octadecane, 3-ethyl-5-(2-ethylbutyl),  1-monolinoleoylglycerol trimethylsilyl ether, 1.1.3.3.5.5.7.7.9.9-decamethyl-9-(2-methyl propoxy)pentasiloxane, 2-cyclohexen-1-one, 4-(hydroxybutyle)-3.5.5-trimethyl, octasiloxane, 1.1.3.3.5.5.7.7.9.9.11.11.13.13.15.15-hexadecamethyl and 3-eicosene. Eight chemical alkaloids constituents have been identified from methanolic extract of the Nerium oleander.

 

Key words: Alkaloids, methanol, gas chromatography-mass spectroscopy (GC-MS) analysis, Nerium oleander. 

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