Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Anti-inflammatory activity of Aconitum heterophyllum on cotton pellet-induced granuloma in rats

Santosh Verma1, Shreesh Ojha2 and Mohammad Raish3*
1S. D. College of Pharmacy, Muzaffarnagar, UP, India. 2Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India. 3Division of Biosciences, Jamia Millia Islamia, New Delhi, India.
Email: [email protected]

  •  Accepted: 02 June 2010
  •  Published: 04 August 2010

Abstract

The anti-inflammatory activity of ethanolic root extract of Aconitum heterophyllum(225, 450 and 900 mg/kg p.o) has been evaluated in cotton pellet-induced granuloma in rats. The extract has reduced inflammation as evidenced by decreased weight of cotton pellet in cotton pellet-induced granuloma in rats. The results demonstrate the anti-inflammatory properties of extract and the effects were comparable to diclofenac sodium, a standard non-steroidal anti-inflammatory drug.  

 

Key words: Aconitum heterophyllum, cotton-pellet, inflammation.

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