Abstract

In the present study, clinical efficacy of herbal coded formulation (Hypoff) as treatment of essential hypertension was investigated. This was case control multicenter prospective randomized authentic allopathic control clinical trial. Open randomized descriptive study was employed in this study. The drug Hypoff was prescribed to test group while Captopril was prescribed to control group who were registered at Qasmi Clinic located at Orangi Town, North Nazimabad and Gulshan-e-Iqbal at Karachi. They all belong to urban population of Karachi. The age range of patients was 25 to 70 years. The response of the treatment on symptomatology of essential hypertension was analysed. Hypoff was found to be an economical, safe and effective drug for essential hypertension treatment and was statistically significant at P<0.03.

Key words: Hypoff, Captopril, clinical trial, efficacy.