Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3785

Full Length Research Paper

Significant pathway analysis of Arabidopsis thaliana fodllowing treatment with paraquat (PQ)

Erhua Rong1, Zhiguo Zhao1, Weidong Zang2, Pingyi guo1, Jinhua Zhang1, Weifeng Zhao1, Meichen Feng1, Lishan Wang2, Dongli Xie2 and Wude Yang1*
1Agronomy College, Shanxi Agricultural University, Taigu, Shannxi 030801, China. 2Department of Biology, Shanghai Jiaotong University, Dongchuan Road, Shanghai, 200241, China.
Email: [email protected]

  •  Published: 09 March 2012


Paraquat (PQ), as a non-selective herbicide, has been used worldwide for weed control in agriculture. However, some medicine plant would be also weeded in this process. Thereby, herbicide antidote is advocated. In this study, we performed two pathway analysis methods, namely, component-based approaches and protein-protein interaction (PPI)-based approach, to identify more significant pathways associated with PQ application. The results showed that eight pathways were identified in component-based analysis, but twenty-two pathways were in PPI-based approach. Among them, phenylalanine metabolism and ribosome pathways were significant in two analysis methods. We anticipate that more PQ antidote would be developed based on our analysis.

Key words: Paraquat, significant pathway enrichment, Arabidopsis thaliana.