Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Effect of green tea on angiotensin II level and myocardial microstructure in spontaneous hypertensive rats

Y. R. Liang1, J. Y. XU1, X. Y. Luo2, X. Q. Zheng3, Q. L. Sun1, S. C. Ma1 and J. L. Lu1*
1Zhejiang University Tea Research Institute, Hangzhou 310029, China. 2Tea Research Institute, Academy of Agricultural Science of Guizhou Province, Guiyang 550006, China. 3Key Laboratory of Horticultural Plants Growth, Development and Biotechnology, Agricultural Ministry of China, Hangzhou 310058, China.
Email: [email protected]

  •  Accepted: 28 July 2010
  •  Published: 18 September 2010

Abstract

Effects of green tea on blood pressure, level of plasma angiotensin II (Ang II) and ultrastructure of left ventricular tissue in spontaneous hypertensive rats (SHR) were investigated. Intragastric administration at dosages 0.2 and 1.0 g kg-1 d-1 green tea significantly decreased blood pressure and plasma Ang II level, accompanying the improvement of ultra structures of left ventricular mitochondrion and myofibrillae. It is considered that the effect of green tea on hypertension might be related to its inhibition of angiotensin converting enzyme.

 

Key words: Green tea, hypertension, spontaneous hypertensive rats, angiotensin, ultra structure, left ventricular, mitochondrion, myofibril.

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