The essential oils of Sedum pallidum is obtained by hydro distillation and analyzed by (GC/MS) for determining their chemical composition and identification of their chemo types. The major component was Hexadecanoic Acid (33.5%), other predominant components were Phenol (9.96%), Eicosane (9.19%), Cyclotrisiloxane, hexamethyl (4.78%), Oxime-methoxy-phenyl (4.34%), Neophytadiene (4.32%), Phytol (3.86%), 3-alpha H-2- Oxofurano (2.78%). The extract of Sedum pallidum (400 mg/disc) showed moderate activity against three bacteria. The zone of inhibition against Proteus mirabilis, Enterobacter Cloacae andStaphylococcus aureus was 10.11 and 18 mm diameter, respectively. But, the extract of S. pallidum was not activity against on Bacillus subtillis and Klebsiella pneumonia. The positive control, Ampicilin, Gentamicine and Stereptomaicin had shown zone of inhibition resistant of all bacterial. The brine shrimp lethality activities of ethanolic extracts of S. pallidum were evaluated in this study. The results of cytotoxic activity of these extracts were more active against brine shrimp lethality of Artemia salina.
Key words: Sedum pallidum, essential oil, antibacterial activity, brine shrimp lethality.
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