Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

Full Length Research Paper

Antimicrobial activities of plumeria acutifolia

Rasool S. N1, Jaheerunnisa S2, Suresh Kumar Chitta3*and Jayaveera K. N4    
1Department of Biotechnology, Jawaharlal Nehru Technological University, Hyderabad, India. 2Department of Microbiology, National Post Graduate College and Research Centre, Nandyal, A. P., India. 3Department of Biochemistry, S. K. University, Anantapur, India. 4Department of Chemistry, JNTU College of Engineering, Anantapur, India.    
Email: [email protected]

  •  Accepted: 20 March 2008
  •  Published: 30 April 2008

Abstract

Ethanolic extract of Plumeria acutifolia Poir. (Apocynaceae) stembark was tested for antimicrobial activity against Gram-positive bacteria (Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus), Gram-negative bacteria (Escherichia coli, Klebsiella Pnumoniae, Psuedomonas aeruginosa, Salmonella typhimurium) and fungi (Aspergillus niger and candida albicans) by disc diffusion method. Minimal inhibitory concentration (MIC) and acute toxicity were also assayed. The ethanol extract showed the strong in vitro antimicrobial activity against E. faecalis, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, A. niger and C. albicans. The extract did not show any toxic symptoms against the tested mice.

 

Key words: Plumeria acutifolia Poir, antibacterial activity, antifungal activity, disc diffusion, M.I.C, M.B.C/M.F.C, acute toxicity.

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