Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3831

Full Length Research Paper

In vitro antitumor and antioxidant activities of Belamcanda chinensis (L.) DC

Mingchuan Liu, Shengjie Yang, Linhong Jin, Deyu Hu, Wei Xue, Song Yang*
State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P.R. China.
Email: [email protected]

  •  Accepted: 19 April 2012
  •  Published: 10 November 2012

Abstract

The in vitro antitumor activities of petroleum ether, ethyl acetate and methanol extracts ofBelamcanda chinensis (L.) DC root were studied against the PC3, Bcap-37, and BGC-823 cell lines. The 1,1-diphenyl-2-picrylhydrazyl free radical (DPPH) free radical scavenging effects of these crude extracts were also tested. The results revealed that ethyl acetate extract and its isolated fractions exhibited significant antitumor activities against the three cell lines. In addition, ethyl acetate extracts exhibited moderate DPPH free radical scavenging effects. The role of these plant extracts in the traditional treatment of tumor in humans is highlighted.

 

Key words: Belamcanda chinensis (L.) DC, ethyl acetate extract, antitumor, 1,1-diphenyl-2-picrylhydrazyl (DPPH