Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Comparative antimicrobial activity of Acacia nilotica L. leaves extracts against pathogenic bacteria and fungi

Amjad ur Rahman*
  • Amjad ur Rahman*
  • Department of Plant Sciences, Quaid-i-Azam University, Islamabad-Pakistan
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Abdul Shakoor
  • Abdul Shakoor
  • Department of Plant Sciences, Quaid-i-Azam University, Islamabad-Pakistan
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Gul Zaib
  • Gul Zaib
  • Department of Microbiology, Quaid-i-Azam University, Islamabad-Pakistan
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Abdul Samad Mumtaz
  • Abdul Samad Mumtaz
  • Department of Plant Sciences, Quaid-i-Azam University, Islamabad-Pakistan
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Yasir Ihtesham
  • Yasir Ihtesham
  • Department of Botany, Hazara University, Mansehra-Pakistan.
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Abdul Aziz Napar
  • Abdul Aziz Napar
  • Department of Plant Sciences, Quaid-i-Azam University, Islamabad-Pakistan.
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  •  Received: 25 February 2012
  •  Accepted: 22 March 2012
  •  Published: 03 August 2014

Abstract

The comparative in vitro antimicrobial activity of ethanol and chloroform leaves extracts from Acacia nilotica L. was studied. Leaves extracts exhibited considerable bacteriostatic activity against two Gram-positive and three Gram-negative strains. The antimicrobial action was compared with the effect of doxycycline antibiotic. The maximum zone of inhibition of 29 mm diameter was observed in Escherichia coli with ethanol extract while a minimum 8 mm zone of inhibition was found in Bacillus subtilis. Klebsiella pneumoniae showed marked resistance towards both ethanol and chloroform extracts. Among the fungal strains tested, Aspergillus flavus exhibited maximum sensitivity action of the extracts. This analysis revealed the high antimicrobial activity in the ethanol extract of A. nilotica L. than chloroform extract. It is recommended to isolate, identify and integrate the bioactive principle in these pathogens management.

 

Key words: Acacia nilotica L., ethanol, extract, chloroform, pathogenic, minimum inhibitory concentration (MIC).

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This article is published under the terms of the Creative Commons Attribution License 4.0

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