Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3804

Full Length Research Paper

In vitro antimicrobial activity of the chemical constituents of Cirsium arvense (L). Scop

Zia Ul Haq Khan1, Shafiullah Khan2, Yongmei Chen1 and Pingyu Wan1*
1School of Science, Beijing University of Chemical Technology, Beijing, 100029, China. 2School of Material Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Email: [email protected] or [email protected]

  •  Accepted: 25 June 2013
  •  Published: 03 July 2013


Anti-bacterial and anti-fungal activities of the isolated constituents from Cirsium arvense were evaluated. These five compounds namely α-tocopherol, 9, 12, 15-octadecatrienoic acid, tracin, hispidulin and luteolin were isolated from the ethyl acetate soluble fraction of the methanolic extract of the plant. Their structures have been identified by electrochemical impedance spectroscopy (EIS), high resolution resonance ionization mass spectrometry (HR-EIMS), 1H-NMR and 13C-NMR spectroscopic methods. The antibacterial and antifungal activities of these compounds were tested; compounds 3, 4 and 5 shows good activities. 

Key words: Cirsium arvense, fractionation, isolation, antibacterial activity, antifungal activity.