Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Flavonoids from the rhizomes of Elephantorrhiza elephantina and Pentanisia prunelloides

S. J. Mpofu1, T. A. M. Msagati2* and R. W. M. Krause3  
1Department of Applied Chemistry University of Johannesburg, Doornfontein Campus, P. O. Box 17011, Johannesburg 2028, South Africa. 2College of Science, Engineering and Technology, University of South Africa, Nanotechnology and Water Sustainability, UNISA Science Campus, Corner of Christiaan de Wet Road & Pioneer Avenue, Florida, 1710  Johannesburg, South Africa. 3Department of Chemistry, Rhodes University, Grahamstown, 6140, South Africa.  
Email: [email protected]

  •  Received: 04 November 2013
  •  Accepted: 24 April 2015
  •  Published: 25 April 2015

Abstract

This paper is reports on the isolation of flavonoid compounds from two medicinal plant species that are widely used in Southern Africa, Elephantorrhiza elephantina and Pentanisia prunelloides which belong to families Fabaceae and Rubiaceae, respectively.  The identification and comparative analysis of flavonoids in E. elephantina and P. prunelloides as well as the structural elucidation of flavonoids were performed using liquid-chromatography electron-spray ionization mass spectroscopy (LC-ESI-MS) and spectroscopic techniques such as Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR). Among the flavonoids identified include epigallocatechin gallate (EGCg), epicatechin (EC), quercetin, epicatechin gallate (ECg), kaempferol and their polymeric derivatives. The analysis revealed that, P. prunelloides contain more flavonoids (0.81%) than E. elephantina (0.77%). 2,2-Diphenylpicrylhydrazyl (DPPH) radical antioxidant tests confirmed the presence of these compounds.

 

Key words: Flavonoids, Fabaceae, Rubiaceae, liquid-chromatography electron-spray ionization mass spectroscopy (LC-ESI-MS).

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This article is published under the terms of the Creative Commons Attribution License 4.0

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