Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3843

Full Length Research Paper

Effect of intracanal administration of association between calcium hydroxide paste and capsaicin in the periapical region of dog’s teeth

Nair Narumi Orita Pavan1*, Marina Viudes Bruder1, Ciomar Aparecida Bersani Amado2, Eduardo Grossmann3, Luz Marina Hernandes4 and Roberto Kenji Nakamura Cuman2    
1Department of Dentistry, State University of Maringá, Maringá, Paraná, Brasil 2Department of Pharmacology, State University of Maringá, Maringá, Paraná, Brazil. 3Department of Morphological Science, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil 4Department of Morphological Science, State University of Maringá, Maringá, Paraná, Brazil.      
Email: [email protected], [email protected]

  •  Accepted: 24 October 2012
  •  Published: 03 March 2013

Abstract

The aim of this study was to histologically examine the periapical region of dog teeth with regard to the inflammatory and resorptive effects of 0.025 and 0.05% capsaicin whenintroduced into the root canal. Fifty-four root canals were prepared and filled with the following: Group I (calcium hydroxide paste; control group), Group II (0.025% capsaicin andcalcium hydroxide paste), and Group III (0.05% capsaicin and calcium hydroxide paste).Serial sections of the teeth were prepared for histomorphological descriptive analysis of the periapical region at 7, 14, and 30 days. The results presented a favorable diagnosis, in which resorption and inflammation were found in all groups, followed by tissue repair.

 

Key words: Capsaicin, calcium hydroxide, inflammation.

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