Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Antioxidant potential of various parts of Ferula assafoetida L.

M. Zia-UL-Haq1*, Shakir Ahmad Shahid2, Shakeel Ahmad3, Mughal Qayum4 and Inamullah Khan5
1Research Institute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Karachi, Karachi-75270, Pakistan. 2Department of Chemistry, University of Sargodha, Sargodha-40100, Pakistan. 3Department of Agronomy, Bahauddin Zakariya University, Multan-60800, Pakistan. 4Department of Pharmacy, Abdul Wali Khan University, Mardan 23200, Pakistan. 5Department of Pharmacy, University of Peshawar, Peshawar-25120, Pakistan.
Email: [email protected]

  •  Accepted: 04 February 2012
  •  Published: 30 April 2012

Abstract

Ferula assafoetida Linn, (Apiaceae) is used in herbal medicine globally for cure and prevention of many diseases. Current research has been carried out to investigate antioxidant potential of this plant. Results indicated that sufficient amount of total phenolic contents and total flavonoid contents are present in its leaves, flowers and seeds. Some top-benched bioassays like 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) free radical scavenging activity, hydroxyl radical scavenging activity, nitric oxide scavenging activity and superoxide radical scavenging activity confirmed the radical scavenging and antioxidant potential of this plant. Since F. assafoetida hold immense therapeutic potential besides food uses, its usage in dietary supplementation can be exploited largely as a functional food.

 

Key words: Ferula assafoetida, total phenolic contents, antioxidant potential, Pakistan.