Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3693

Full Length Research Paper

Caryocar brasiliense fruit intake ameliorates hepatic fat deposition and improves intestinal structure of rats

Lauane Gomes Moreno
  • Lauane Gomes Moreno
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
  • Google Scholar
Lidiane Guedes Oliveira
  • Lidiane Guedes Oliveira
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
  • Google Scholar
Dirceu Sousa Melo
  • Dirceu Sousa Melo
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
  • Google Scholar
Liliane Vanessa Costa Pereira
  • Liliane Vanessa Costa Pereira
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
  • Google Scholar
Karine Beatriz Costa
  • Karine Beatriz Costa
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
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Joao Luiz Miranda
  • Joao Luiz Miranda
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
  • Google Scholar
Etel Rocha Vieira
  • Etel Rocha Vieira
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
  • Google Scholar
Flvio Castro Magalhes
  • Flvio Castro Magalhes
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
  • Google Scholar
Marco Fabricio Dias-Peixoto
  • Marco Fabricio Dias-Peixoto
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
  • Google Scholar
Elizabethe Adriana Esteves*
  • Elizabethe Adriana Esteves*
  • Programa Multicêntrico de Pós-graduação em Ciências Fisiológicas Universidade Federal dos Vales do Jequitinhonha e Mucuri, Brazil.
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  •  Received: 09 August 2016
  •  Accepted: 19 September 2016
  •  Published: 03 October 2016

Abstract

Caryocar brasiliense (pequi) is an exotic fruit, high in monounsaturated fat acids (MUFA) and bioactive compounds, which have beneficial effects on cardiometabolic risk factors. However, this fruit is poorly studied in this context. In this study, the effects of pequi pulp intake on cardiometabolic risk factors of rats were evaluated. Therefore, 16 male weaned rats were divided into two groups: Control group and Pequi group. Control group was feed a standard diet and pequi group, the same diet added pequi pulp (3.26 g.100-1) for 15 weeks. At the end, plasma lipids, glucose, insulin, Homeostasis Model Assessment of Insulin Resistance index (HOMA-IR), blood pressure, heart rate, hepatic and fecal lipids and intestinal histomorphometric parameters were accessed. Liver and heart samples were harvested for redox status assays. There were no differences between experimental groups for blood pressure, heart rate, glucose, insulin, HOMA-IR, triglycerides, cholesterol, HDL-cholesterol, and liver and heart redox status (p<0.05). Pequi group had lowered lipid hepatic deposition and increased fecal output (p<0.05), increased intestinal villus height and crypt depth. Thus, pequi pulp intake minimized liver fat deposition by increasing its intestinal output and improved intestinal structure of rats, which can contribute for reducing cardiometabolic risk factors. MUFA, carotenoids and fibres can be associated, at last in part, with these effects.

Key words: Caryocar brasiliense, pequi, cardiometabolic risk, lipid metabolism, redox status.