Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Isolation, chemical characterization and in vitro antioxidant activities of polysaccharides from Aconitum coreanum

Bin Li1*, Xian-Jun Meng1 and Li-Wei Sun2
1College of Food Science, Shenyang Agricultural University, Shenyang 110866, China. 2College of Basic Medical, Beihua University, Jilin City 132013, China.
Email: [email protected]

  •  Accepted: 30 November 2011
  •  Published: 09 February 2012

Abstract

The water-soluble crude polysaccharide Aconitum coreanum polysaccharides (ACPS) was extracted from A. coreanum and purified by Diethylaminoethyl cellulose and Sepharose CL-6B chromatography, giving three polysaccharide fractions coded as ACPSA-1, ACPSB-2 and ACPSB-3. Their chemical and physical characteristics of polysaccharide fractions, and antioxidant capacity, including scavenging activity against DPPH radicals, superoxide and hydroxyl radicals, and chelating ability, were valuated in this paper. Experiment results showed that ACPS-2 and ACPS-3 exhibited significantly antioxidant activity at a concentration-dependent manner. The polysaccharide fractions can be developed as new antioxidant agents.

 

Key words: Aconitum coreanum, polysaccharide, purification, characterization, antioxidant activity.

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