Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3818

Full Length Research Paper

Effect of Cinnamon zeylanicum essence and distillate on the clotting time

Nazari Hossein1,2 , Zohrvand Zahra1 , Mohammadi Abolfazl2, Safaryeh Mahdi1 and Khaleghian Ali2,3
1University of Applied Sciences and Technology Education Center, Semnan branch,Semnan, Iran. 2Biochemistry and Hematology Department, Semnan, Faculty of Medicine, Semnan University of Medical Sciences, Iran. 3Tehran University, Biochemistry and Biophysics Institute, Tehran, Iran.
Email: [email protected]

  •  Accepted: 26 April 2013
  •  Published: 17 May 2013


A plant called medicinal herb is one in which some special materials are constructed and stored in its configuration which are called effective materials. Active materials are made during a chain of special and complex biochemical processes which are known as second metabolites. The scientific name of Cinnamon is Cinnamomum zeylanicum from Lauraceaeis. Physiological effect of Cinnamon is related to essence and tannins. Cinnamon reinforces properties of digestion function and blood stream circulation. Cinnamon has one of the highest antioxidant levels of any species. Also, Cinnamon supports sugar metabolism and helps maintain the healthy blood sugar levels as well as contributes to healthy circulation and heart function. The aim of this study was to determine the effect of the effective materials of Cinnamon herbal plants on blood clotting time. Water and methanol extracts, essence and distillate of Cinnamon were provided by Soxhelt and Clevenger devices after collecting. The test of blood coagulation time determination was studied through tube test method with all of the samples. The results indicate that the blood clotting time significantly decreased in the presence of Cinnamon distillate and the essential oil in comparison with control. But Cinnamon water extracts do not have effect on blood coagulation time. There are significant differences between the water extract of cinnamon and its essence at the level of 5% (P < 0.05) as well as between the distillate and the water extract significantly up to 1% (P < 0.01). Among the existing data in this study, the distillate and essential oil of Cinnamon have coagulation stronger effects than water and hydro alcoholic extract. These may be particularly useful in situations where the wound is not clotting, which can be due to external factors such as the size of wound, or medical factors like hemophilia.


Key words: Essential oil, cinnamon extracts, distillate, blood coagulation, gas chromatography/mass spectrometry (GC/MS).