A plant called medicinal herb is one in which some special materials are constructed and stored in its configuration which are called effective materials. Active materials are made during a chain of special and complex biochemical processes which are known as second metabolites. The scientific name of Cinnamon is Cinnamomum zeylanicum from Lauraceaeis. Physiological effect of Cinnamon is related to essence and tannins. Cinnamon reinforces properties of digestion function and blood stream circulation. Cinnamon has one of the highest antioxidant levels of any species. Also, Cinnamon supports sugar metabolism and helps maintain the healthy blood sugar levels as well as contributes to healthy circulation and heart function. The aim of this study was to determine the effect of the effective materials of Cinnamon herbal plants on blood clotting time. Water and methanol extracts, essence and distillate of Cinnamon were provided by Soxhelt and Clevenger devices after collecting. The test of blood coagulation time determination was studied through tube test method with all of the samples. The results indicate that the blood clotting time significantly decreased in the presence of Cinnamon distillate and the essential oil in comparison with control. But Cinnamon water extracts do not have effect on blood coagulation time. There are significant differences between the water extract of cinnamon and its essence at the level of 5% (P < 0.05) as well as between the distillate and the water extract significantly up to 1% (P < 0.01). Among the existing data in this study, the distillate and essential oil of Cinnamon have coagulation stronger effects than water and hydro alcoholic extract. These may be particularly useful in situations where the wound is not clotting, which can be due to external factors such as the size of wound, or medical factors like hemophilia.
Key words: Essential oil, cinnamon extracts, distillate, blood coagulation, gas chromatography/mass spectrometry (GC/MS).
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