Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

In vitro anti-oxidant activity of Lespedeza cuneata methanolic extracts

Ju-Sung Kim1 and Myong-Jo Kim1,2*
1Oriental Bio-herb Research Institute, Kangwon National University, Chuncheon 200-701, South Korea. 2Division of Bio-resources Technology, Kangwon National University, Chuncheon 200-701, South Korea.
Email: [email protected]

  •  Accepted: 19 March 2010
  •  Published: 18 April 2010

Abstract

In this study, the anti-oxidant activities of Lespedeza cuneata extract and fractions were evaluated by various in vitro assays, including electron donation ability (EDA) assay, reducing power, ferric thiocyanate (FTC) and thiobarbituric acid (TBA) tests. The electron donation ability of the ethylacetate fraction (95%) demonstrated stronger activity than butylated hydroxyanisole (16%). The ethylacetate fraction (OD700 = 0.68) also exhibited the strongest reducing power. Total phenol and flavonoid content were highest in the ethylacetate fraction (359.54 mg GAE/g and 209.63 mg QE/g, respectively). Methanolic extracts had greater anti-lipid peroxidative effects than that of an identical concentration of butylated hydroxyanisole. This result suggests the potential of development of useful natural anti-oxidants.

 

Key words: Electron donation ability, ferric thiocyanate method, Lespedezacuneata, reducing power, thiobarbituric acid test.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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