Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Brown macroalgae: Promising sources of bioactive products against human herpesviruses

Maria Leonisa Sanchez Nunez
  • Maria Leonisa Sanchez Nunez
  • Programa de Pós-graduação em Ciências e Biotecnologia, Instituto de Biologia, Universidade Federal Fluminense - Campus do Valonguinho, Niterói, RJ, CEP 24210-130, Brasil.
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Vitor Won-Held Rabelo
  • Vitor Won-Held Rabelo
  • Programa de Pós-graduação em Ciências e Biotecnologia, Instituto de Biologia, Universidade Federal Fluminense - Campus do Valonguinho, Niterói, RJ, CEP 24210-130, Brasil.
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Izabel Christina Nunes de Palmer Paixao
  • Izabel Christina Nunes de Palmer Paixao
  • Programa de Pós-graduação em Ciências e Biotecnologia, Instituto de Biologia, Universidade Federal Fluminense - Campus do Valonguinho, Niterói, RJ, CEP 24210-130, Brasil.
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Valeria Laneuville Teixeira
  • Valeria Laneuville Teixeira
  • Programa de Pós-Graduação em Biodiversidade Neotropical, Instituto de Biociências, Urca, Rio de Janeiro, RJ, 22290-255, Brasil.
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  •  Received: 22 September 2021
  •  Accepted: 22 February 2022
  •  Published: 31 March 2022

Abstract

Marine brown macroalgae have stood out as important sources of new bioactive products, such as antimicrobial, anticoagulant, anti-inflammatory and antiviral drugs. This study aimed to review the literature on the applications of products derived from brown macroalgae as antiviral agents against human herpesviruses. To date, species of seven distinct orders of brown algae have been studied for this purpose, such as Fucales (19 species), Dictyotales (14 species), Ectocarpales (9 species), Laminariales (2 species), Scytothamnales (1 species), Sphacelariales (1 species) and Tilopteridales (1 species). The products evaluated in this review include extracts, fractions and isolated natural products, mainly terpenoids. Extracts, fractions and isolates of brown algae were evaluated against four viruses: simple herpesviruses types 1 and 2 (HSV-1 and HSV-2), human cytomegalovirus (HCMV) and Epstein–Barr Virus (VEB), also known as human herpesvirus 4 (HHV-4). This review shows products derived from brown macroalgae as potential antiherpetic agents.

Key words: Brown algae, antiviral, marine natural products.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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