Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3750

Article in Press

Metabolic profile of wistar rats after consumption of flour prepared with grains and fruits

Barbara Bucalem, Barbara Geraldo Amaro, Bruna Gomes Prado, Julia Novacki, Sandra Maria Barbalho1, Élen Landgraf Guiguer, Maricelma da Silva Soares de Souza, Manuela dos Santos Bueno, Adriano Cressoni Araújo, Raul José Girio and Patrícia Cincotto dos Santos Bueno

  •  Received: 25 January 2021
  •  Accepted: 25 June 2021
The occurrence of chronic and degenerative diseases, such as obesity, diabetes, cardiovascular disease (CVD), and cancer is increasing sharply. In the last years, there has been an increase in interest in the consumption of foods with functional properties that are related to weight loss and disease prevention. For these reasons, this study aimed to evaluate the effects of flour prepared with grains and fruits on the metabolic profile of Wistar rats. Female rats were randomly divided into four groups: G1: control group; G2: animals that received condensed milk and sugar; G3: animals that received food supplemented with a mixture of powdered grains and fruits; G4: animals that received condensed milk, sugar and rat food supplemented with a mixture of powdered grains and fruits. Our results showed that the use of the flour of grains and fruits promoted a significant reduction in abdominal circumference, visceral fat, and triglycerides levels in the animals from G3 compared with G1. However, the use of the flour of grains and fruits can be beneficial in association with a balanced diet. When the association is carried out at the same time that there is the consumption of foods rich in sugars, the beneficial effects were not observed.

Keywords: obesity, grains, fruits, cardiovascular disease