Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3749

Full Length Research Paper

Pharmaceutical topical gel containing proanthocyanidin polymers-rich fraction from Stryphnodendron adstringens

Marco Antonio Costa
  • Marco Antonio Costa
  • Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Maringá, PR, Brazil.
  • Google Scholar
Andressa Blainski
  • Andressa Blainski
  • Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Maringá, PR, Brazil.
  • Google Scholar
Vanessa Kaplum
  • Vanessa Kaplum
  • Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Maringá, PR, Brazil.
  • Google Scholar
Marli Miriam de Souza Lima
  • Marli Miriam de Souza Lima
  • Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Maringá, PR, Brazil.
  • Google Scholar
Tania Ueda-Nakamura
  • Tania Ueda-Nakamura
  • Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Maringá, PR, Brazil.
  • Google Scholar
Benedito Prado Dias Filho
  • Benedito Prado Dias Filho
  • Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Maringá, PR, Brazil.
  • Google Scholar
Joao Carlos Palazzo de Mello
  • Joao Carlos Palazzo de Mello
  • Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Maringá, PR, Brazil.
  • Google Scholar
Celso Vataru Nakamura
  • Celso Vataru Nakamura
  • Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Maringá, PR, Brazil.
  • Google Scholar


  •  Received: 19 December 2017
  •  Accepted: 22 March 2018
  •  Published: 24 March 2018

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Fidel PL (2007). History and update on host defense against vaginal candidiasis. Am. J. Reprod. Immunol. 57:2-12.
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Freitas ALD, Kaplum V, Rossi DCP, Silva LBR, Melhem M de SC, Taborda CP, Mello JCP, Nakamura CV, Ishida K (2018). Proanthocyanidin polymeric tannins from Stryphnodendron adstringens are effective against Candida spp. isolates and for vaginal candidiasis treatment. J. Ethnopharmacol. 216:184-190.
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Hernandes L, Silva Pereira LM, Palazzo F, Mello JCP (2010). Wound-healing evaluation of ointment from Stryphnodendron adstringens (barbatimãoo) in rat skin. Braz. J. Pharm. Sci. 46:431-436.
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ICH (2005). Q2 (R1): Validation of analytical procedures: text and methodology. In International Conference on Harmonization, Geneva.

 

Ishida K, Mello JCM, Garcia Cortez DA, Dias Filho BP, Ueda-Nakamura T, Nakamura CV (2006). Influence of tannins from Stryphnodendron adstringens on growth and virulence factors of Candida albicans. J. Antimicrob. Chemother. 58(5):942-949.
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Ishida K, Rozental S, Mello JCP, Nakamura CV (2009). Activity of tannins from Stryphnodendron adstringens on Cryptococcus neoformans: effects on growth, capsule size and pigmentation. Ann. Clin. Microbiol. Antimicrob. 8(1):29.
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Isler AC, Lopes GC, Cardoso MLC, Mello JCP, Marques LC (2010). Development and validation of a LC-method for the determination of phenols in a pharmaceutical formulation containing extracts from Stryphnodendron adstringens. Quim. Nova 33:1126-1129.
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Lopes GC, Sanches ACC, Nakamura CV, Dias Filho BP, Hernandes L, Mello JCP (2005). Influence of extracts of Stryphnodendron polyphyllum Mart. and Stryphnodendron obovatum Benth. on the cicatrisation of cutaneous wounds in rats. J. Ethnopharmacol. 99:265-272.
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Lopes GC, Vieira Machado FA, Mendes de Toledo CE, Sakuragui CM, Mello JCM (2008). Chemotaxonomic significance of 5-deoxyproanthocyanidins in Stryphnodendron species. Biochem. Syst. Ecol. 36:925-931.
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Luiz RLF, Vila TVM, Mello JCP, Nakamura CV, Rozental S, Ishida K (2015). Proanthocyanidins polymeric tannin from Stryphnodendron adstringens are active against Candida albicans biofilms. BMC Complement. Altern. Med. 15:68.
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Luize PS, Tiuman TS, Morello LG, Maza PK, Ueda-Nakamura T, Dias Filho BP, Cortez DAG, Mello JCP, Nakamura CV (2005). Effects of medicinal plant extracts on growth of Leishmania (L.) amazonensis and Trypanosoma cruzi. Rev. Bras. Ciênc. Farm. 41:85-94.

 

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