Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Hypoglycemic activity in diabetic rats of stigmasterol and sitosterol-3-O-β-D-glucopyranoside isolated from Pseuderanthemum palatiferum (Nees) Radlk. leaf extract

Somsak Nualkaew*
  • Somsak Nualkaew*
  • Department of Pharmaceutical Sciences, Faculty of Pharmacy, Mahasarakham University, Mahasarakham 44150 Thailand.
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Peerawit Padee
  • Peerawit Padee
  • Department of Medical Services, Jungharn Hospital, Roi Et Provincial of Public Health, Roi Et 45000 Thailand.
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Chusri Talubmook
  • Chusri Talubmook
  • Department of Biology, Faculty of Sciences, Mahasarakham University, Mahasarakham 44150 Thailand.
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  •  Received: 29 December 2014
  •  Accepted: 20 May 2015
  •  Published: 25 May 2015

References

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Eidi A, Eidi M, Esmaeili E (2006). Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats. Phytomedicine 13:624-629.
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Ivorra MD, D'Ocon MP, Paya M, Villa A (1998). Anti-hyperglycemic and insulin releasing effects of beta-sitosterol-3-beta-D-glucoside and its aglycone, beta-sitosterol. Arch. Int. Pharmacodyn. Ther. 296:224-231.
 
Ivorra MD, Paya M, Villa A (1990). Effect of beta-sitosterol-3-beta-D-glucoside on insulin secretion in vivo in diabetic rats and and in vitro in isolated rat islets of Langerhans. Pharmazie 4:271-273.
 
Jamal AK, Yaacob WA, Din LB (2009). A chemical study on Phyllanthus Columnaris. Eur. J. Sci. Res. 28:76-81.
 
Jamaluddin F, Mohamed S, Lajis MN (1994). Hypoglycaemic effect of Parkia speciosa seeds due to the synergistic action of β-sitosterol and stigmasterol. Food Chem. 49(4):339-345.
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Jayaprakasha GK, Jadegoud Y, Gowda GAN, Patil BS (2010). Bioactive compounds from sour orange inhibit colon cancer cell proliferation and induce cell cycle arrest. J. Agric. Food Chem. 58:180-186.
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Kongduang D, Wungsintaweekul J, De-Eknamkul W (2008). Biosynthesis of β-sitosterol and stigmasterol proceeds exclusively via the mevalonate pathway in cell suspension cultures of Croton stellatopilosus. Tetrahedron Lett. 49:4067-4072.
Crossref
 
Padee P, Nualkeaw S (2009). Current information of medicinal plants: Pseuderanthemum palatiferum (Nees) Radlk. J. Health Sci. 8:131-138.
 
Padee P, Nualkeaw S, Talubmook C, Sakuljaitrong S (2009). Acute toxicity and sub-acute toxicity of Pseuderanthemum palatiferum (Nees) Radlk. leaf extract. Isan. J. Pharm. Sci. 5:74-81.
 
Padee P, Nualkeaw S, Talubmook C, Sakuljaitrong S (2010). Hypoglycemic effect of a leaf extract of Pseuderanthemum palatiferum (Nees) Radlk. in normal and streptozotocin-induced diabetic rats. J. Ethnopharmacol. 132:491-496.
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Panda S, Jafri M, Kar A, Meheta BK (2009). Thyroid inhibitory, antiperoxidative and hypoglycemic effects of stigmasterol isolated from Butea monosperma. Fitoterapia 80:123-126.
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Perez GRM, Vargas SR (2002). Triterpens for Agarista maxicana as potential anti-diabetic agents. Phytother. Res. 16:55-58.
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Talubmook C (2008). Effect of polysaccharide from Phellinus ignarius (L) Quel. on hematological values and blood cell characteristic in diabetic rats. J. Microscopy Soc. Thailand 22:42-45.

 

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