Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

An investigation of the hepatoprotective potential of Garcinia kola seed extract in an anti-tubercular treatment model

Tweneme Ogono
  • Tweneme Ogono
  • Department of Biochemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
  • Google Scholar
Oluwole Emmanuel Taiwo
  • Oluwole Emmanuel Taiwo
  • Department of Biochemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
  • Google Scholar
Kabiru Usman
  • Kabiru Usman
  • Department of Biochemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
  • Google Scholar
David Adeyemi
  • David Adeyemi
  • Department of Anatomy and Cell Biology, Obafemi Awolowo University, Ile-Ife, Nigeria.
  • Google Scholar
Efere Martins Obuotor
  • Efere Martins Obuotor
  • Department of Biochemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
  • Google Scholar
Francis Adelade Fakoya
  • Francis Adelade Fakoya
  • Department of Anatomical Sciences, St. George?s University School of Medicine, True Blue, St. George?s Grenada, The Caribbean.
  • Google Scholar
Omolaja Osoniyi*
  • Omolaja Osoniyi*
  • Department of Biochemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
  • Google Scholar


  •  Received: 27 May 2014
  •  Accepted: 09 October 2014
  •  Published: 10 October 2014

References

Akintowa A, Essien AR (1990). Protective effects of Garcinia kola Seed extract against Paracetamol Induced hepatotoxicity in rats. J. Ethnopharmacol. 29(2):207-211.
Crossref
 
Adesuyi AO, Elumm IK, Adaramola FB, Nwokocha AGN (2012). Nutritional and Phytochemical Screening of Garcinia kola. Adv. J. Food Sci. Technol. 4(1):9-14.
 
Bradford MM (1976). A rapid and sensitive method for the quantification of microgram quantities of protein, utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
Crossref
 
Centers for Disease Control and Prevention (CDC) (2014). Tuberculosis-Data and Statistics.
 
Collins K, Ahorlu FB (2013). Factors affecting TB case detection and treatment in the Sissala East District, Ghana. J. Tuberc. Res. 1:29-36.
Crossref
 
Deutsche Gesellschaft fur KlinischeChemie (DGKC) (1972). Standardization of methods for measurement of enzymatic activities in biological fluids. Z. Klin. Chem. Klin. Biochem.10:182-192.
 
Drury AA, Wallington EA (1980). Carleton's Histological Technique, 5th Edition. Oxford University Press, New York.
 
Fakoya FA, Osoniyi O, Obuotor EM (2013). Analysis of Combined anti-tuberculous drug induced neurotoxicity in the cerebral cortex of adult wister rats by immune histochemistry. J. Neurosci. Behav. Health 5(2):20-29.
Crossref
 
Farombi EO (2003). African indigenous plants with chemotherapeutic potentials and biotechnological approach to the production of bioactive prophylactic agents. Afr. J. Biotechnol. 2(12):662-671.
 
Frieden TR, Sterling TR, Munsiff SS, Watt CJ, Dye C (2003). Tuberculosis. Lancet 362:887-899.
Crossref
 
Iwu MM, Igboko OA, Onwuchekwa U, Okunji CO (1987). Evaluation of theantihepatotoxicity of the biflavanoids of Garcinia kola seeds. J. Ethnopharmacol 21:127-142.
Crossref
 
Jendrassik L, Grof P (1938). Vereinfachte photometrische methoden zur bestimmung des bilirubin. Biochem. Z. 297:81-89.
 
Kaona FA, Tuba M, Siziya S, Sikaona L (2004). An assessment of factors contributing to treatment adherence and knowledge of TB transmission among patients on TB treatment. BMC Public Health 4:68.
Crossref
 
Kaplowitz N (2001). Drug-induced liver disorders: Implications for drug development and regulation. Drug Saf. 24(7):483-490.
Crossref
 
Konstantinos A (2010). Testing for tuberculosis. Aust. Prescr. 33(1):12-18.
 
Leung CC, Lange C, Zhang Y (2013). Tuberculosis: current state of knowledge; an epilogue. Respirology 18:1047-1055.
Pubmed
 
Lian Y, Zhao J, Xu P, Wang Y, Zhao J, Jia L, Fu Z, Jing L, Liu G, Peng S (2013) Protective Effects of Metallothionein on Isoniazid and Rifampicin-Induced Hepatotoxicity in Mice. PLoS ONE 8(8):e72058.
Crossref
 
Misra HP, Fridovich I (1972). The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 247:3170-3175.
Pubmed
 
Moron MS, Depierre JW, Mannervik B (1979). Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochim. Biophys. Acta 582(1):67-78.
Crossref
 
Parihar MS, Taruma H (2003). Phenolic anti-oxidant attenuate hippocampal neuronal cell damage against Kinic acid induced excitotoxicity. J. Biol. Sci. 28:121-128.
 
Reitman S, Frankel S (1957). A calorimetric method for the determination of serum glutamic oxaloacetic acid and glutamic pyruvic transaminases. Am. J. Clin. Pathol. 28:56-63.
Pubmed
 
Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG (1973). Selenium: biochemical role as a component of glutathione peroxidase. Science 179(73):588-590.
Crossref
 
Saleem TSM, Christina AJM, Chidambaranathan N, Ravi V, Gauthaman K (2008). Hepatoprotective activity of Annonasquamosa Linn. on experimental animal model. Int. J. App. Res. Nat. Prod. 1(3):1-7.
 
Sinha AK (1972). Colorimetric assay of catalase. Anal. Biochem.47:389-394.
Crossref
 
Tostmann A, Boeree MJ, Aarnoutse RE, de Lange WC, van der Ven AJ, Dekhuijzen R (2008). Antituberculosis drug-induced hepatotoxicity: concise up-to-date review. J. Gastroen. Hepatol. 23(2):192-202.
Crossref
 
Wares DF, Singh S, Acharya AK, Dangi R (2003). Non-adherence to tuberculosis treatment in the eastern Tarai of Nepal. Int. J. Tuberc. Lung D. 7:327-335.
Pubmed
 
World Health Organization (WHO) (2003). Treatment of Tuberculosis: Guidelines for National Programmes, 3rd edn. (WHO/CDS/TB/2003.13). Geneva: World Health Organization.
 
World Health Organisation (WHO) (2012). Global tuberculosis report 2012. Geneva, World Health Organization. WHO/HTM/TB/2012.6.
 
Yue J, Peng RX, Yang J, Kong R, Liu J (2004). CYP2E1 mediated isoniazid-induced hepatotoxicity in rats. Acta Pharm. Sin. 25(5):699-704.
Pubmed