February 2018

Antibacterial activity of Ethiopian Lepidium sativum L. against pathogenic bacteria

Lepidium sativum is commonly known as “fetto” in Ethiopia, and a popular herbal plant which is widely used in folk medicine. The objective of this study is to investigate the potential of three different crude solvent extracts from seed of Lepidium sativum (ethanol, methanol and chloroform) against human pathogenic bacterial strains: Escherichia coli (ATCC 25922), Klebsiella pneumoniae (ATCC-27736),...

Author(s): Yohannes Besufekad, Senbeto Beri, Tefera Adugnaw and Kibitu Beyene

February 2018

The antiulcer and antioxidant mechanisms of the butanolic fraction extract obtained from Bauhinia forficata leaves: A medicinal plant frequently used in Brazilian folk medicine

The objectives of this work were to evaluate the antiulcer activity, antioxidant mechanisms, phytochemical analysis and ecotoxicological risk of the butanolic fraction (ButFr) obtained from the leaf extracts of Bauhinia forficata. In an ischemia-reperfusion (IR), gastric ulcer model with doses 12.5 and 6.25 mg kg-1 promoted significant decreases in the ulcerative lesion area (ULA) by 50% (p<0.001) and 46%...

Author(s): Bárbara Gomes Del Rey, Luciana Lopes Guimarães, Marcos Sergio de Toledo, Hélio Kiyoshi Takahashi, Anita Hilda Straus, Monike Silva de Freitas, Bruna Hattebberger, Cláudia Maria Moraes Silva, Matheus Roberti de Carvalho and Walber Toma