February 2019
Aristolochic acids in herbal medicine: Public health concerns for consumption and poor regulation of botanical products in Nigeria and West Africa
Aristolochic acids are naturally occurring biomolecules found in plants of the genus Aristolochia and Asarum belonging to the family Aristolochiaceae. They are reported to be carcinogenic and nephrotoxic; and are implicated in kidney diseases, aristolochic acid nephropathy (AAN) which may result in kidney failure, other health complications and possibly death. Aristolochic acids are highly genotoxic and are linked to...
February 2019
In vitro effect and scanning electron microscopic changes of Nigella sativa loaded chitosan nanoparticles on Schistosoma mansoni adult
Nanoparticles can act as drug carriers that can modulate pharmacokinetics, increase bioavailability and target release with minimal toxic effects. The present work aimed to assess the therapeutic effect and electron microscopic changes of Nigella sativa loaded Chitosan Nanoparticles (NSLCN) on adult Schistosoma mansoni in vitro. Adult worms were removed from the portal and mesenteric veins of infected mice after 90...
February 2019
Effect of hormones on the seed germination of Bupleurum species
In Asia, Radix Bupleuri (Bupleurum spp. root) is an important medicine used for treating many diseases over the past 2000 years. However, its cultivation is difficult due to poor germination rates and loss of seedling viability shortly after seeding. In the present study, the effect of 6-benzyl aminopurine (6-BA), daminozide, gibberellin (GA3), paclobutrazol, uniconazole, and mepiquat chloride (MC) on the germination of...
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