September 2016

Anti-candida biofilm properties of Cameroonian plant extracts

Candida infections can be superficial, invasive or disseminating. The virulence of Candida species has been attributed to several factors, including the promotion of hyphae and biofilm formation, adherence to host tissues, and response to environmental changes and morphogenesis. Resistance to many clinically used antifungal agents has led to the need to identify new compounds and drugs for therapeutic use. Therefore,...

Author(s): Zeuko´o M. Elisabeth, Virginio C. Lopez, Sara M. Soto and Fekam B. Fabrice

September 2016

Antimicrobial activities and preliminary phytochemical tests of crude extracts of important ethnopharmacological plants from Brazilian Cerrado

Screening of native plants with therapeutical effects constitutes a valuable way to enhance biological attributes of medicinal herbs and discover new drugs. Therefore, ethanol and methanol extracts from ten plants collected from Brazilian Cerrado were tested to inhibitory effects against Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923) and Pseudomonas aeruginosa (ATCC 27853) through disc diffusion. The...

Author(s): Caroline N. Maia, Cláudia M. da Silva, Ronaldo R. Júnior, Dario A. Oliveira, Perácio R. B. Ferreira, Carla Soares Godinho, Elio G. Fernandes and Henrique M. Valério

September 2016

Anti-HIV-1 activity in human primary cells and Anti-HIV-1 RT inhibitory activity of extracts from the red seaweed Acanthophora spicifera

First generation drugs such as zidovudine have been extensively used in clinical practice, resulting in the development of HIV resistance to these nucleoside analogs. Several studies have demonstrated the effective anti-HIV activity of natural products derived from seaweeds, suggesting promising sources of substances for the development of novel antiviral drugs. In this paper, the antiviral effect of extracts from the...

Author(s): Caio Cesar Richter Nogueira, Izabel Christina Nunes de Palmer Paixão, Claudio Cesar Cirne-Santos, Paulo Roberto Soares Stephens, Roberto Campos Villaça, Helena de Souza Pereira and Valéria Laneuville Teixeira