September 2012

Co-culturing of Catharanthus roseus, Vinca major and Rauwolfia serpentina cell suspensions in shake flask and bioreactor: Production of a novel alkaloid with antioxidant potential

Conditions for co-culturing the cell suspensions of Catharanthus roseus, Rauwolfia serpentina and Vinca major in shake flask and bioreactor are described here for the possible complementation of the terpenoid indole alkaloid pathway operating in them. Catharanthus + Rauwolfia or Catharanthus + Vinca cell combinations could be reared on a Murashige and Skoog medium containing 2.0 mg...

Author(s): Priyanka Verma, Ajay Kumar Mathur, Singh Arpan, Alka Srivastava, Nusrat Masood, Suaib Luqman, Mohita Upadhyaya and Archana Mathur

September 2012

Free radical scavenging activity and phenolic content of edible wild fruits from Kazdagi (Ida Mountains), Turkey

The ethanolic and acetone extracts of wild fruits collected from Kazdagi (Ida Mountains) were examined for free radical scavenging activity and phenolic compounds. The extracts of the fresh fruits of Arbutus unedo, Lycium europaeum, Prunus spinosa, Rosa canina, andRubus sanctus were examined for their antioxidant properties by using the free radical 1,1’-diphenyl-2-picrylhydrazyl (DPPH)...

Author(s): Gulen Turker, Bayram Kizilkaya , Nazan Cevik and Ahmet Gonuz

September 2012

In-vitro and in-vivo anti-inflammatory activity of Syzygium alternifolium (wt) Walp

The study was aimed to evaluate the analgesic and anti-inflammatory activity (by both in-vitro and in-vivo) of both chloroform and methanol root extracts of Syzygium alternifolium(wt) Walp. Methods used for the studies are In-vitro measurement of 5-lipoxygenase inhibition and in-vivo measurement of rat paw edema and ear edema in rats, acetic acid induced writhing response and heat...

Author(s): Vasu Kandati, P. Govardhan, Ch. Siva Reddy, A. Ravinder Nath and R. R. Reddy

September 2012

Cytotoxic effect of Anisomeles indica extract on human pharynx squamous cancer cells

This study attempted to investigate the inhibitory effect of Anisomeles indica hexane extract (AIE) on the proliferation of FaDu human pharynx squamous cancer cells and the apoptotic effect of this extract on FaDu cells. AIE exhibited significant cytotoxicity toward FaDu cells in a dose- and time-dependent manner (IC50 = 60.1 μg/ml for 24 h treatment and 29.7 mg/ml for 72 h treatment). In comparison,...

Author(s): Hsia-Fen Hsu, Shih-Fan Chang, Zi-Hua Chen, Shyng-Shiou F. Yuan, Yu-Duan Tsai, Chao-Ping Wang, Shih-Wei Wang, Li-Wen Fang and Jer-Yiing Houng,