August 2019

DPPH radical scavenging activity of extracts from Rhamnus prinoides

Hexane, chloroform, ethyl acetate and methanolic extracts from leaves and stem-bark of Rhamnus prinoides were evaluated for their antioxidant activity by DPPH radical scavenging assay. The leaves extracts showed scavenging activity ranging from 03.33±0.89 to 55.03±3.40 µg mL-1 while the stem-bark extracts showed relatively strong scavenging activity ranging from 03.65±1.02 to 59.55±2.27...

Author(s): Manoharan Karuppiah Pillai, Lehlohonolo Isaac Santi and Sibusisiwe Magama

August 2019

Evaluation of cytotoxic activity of triterpenes from Clusia studartiana

Family Clusiaceae is spread throughout tropical as well as temperate zones, presenting many triterpenes, reported as selective antitumoral agents. The aim of this study is to isolate and identify triterpenes from Clusia studartiana C. M. Vieira & Gomes da Silva and evaluate their cytotoxicity in melanoma (SKMEL 28) and myeloid leukemia (K562) cell lines. Thus, the hexanic extract was processed by phytochemical...

Author(s): Lavínia de C. Brito, Marcia V. de Carvalho, Vagner P. da Silva, Alan P. Heringer, Priscila M. da Silva, Ana Paula G. A. Fontão, Maria R. Figueiredo and André Luiz F. Sampaio  

August 2019

Modulatory effects of Momordica balsamina on Th1/Th2 cytokine profiles in immune-challenged rats

There is an ever-growing interest to identify plants that boost the immune system functions. The objective of the present study was to evaluate the immunomodulatory effects of Momordica balsamina (MB) leaves extract in BCG-immunized rats. Thirty rats were randomly divided into five groups (n = 6). MB extract was suspended in 1% carboxymethyl cellulose (CMC).  Firstly, animals were challenged subcutaneously with...

Author(s): Iman H. Abdoon, Bashier Osman, Maowia M. Mukhtar and Hatim Ali Elsheikh  

August 2019

Comparative study of proximate, mineral and phytochemical analysis of the leaves of Ocimum gratissimum, Vernonia amygdalina and Moringa oleifera

The aim of this study is to make a comparative analysis of the proximate, mineral and phytochemical compositions of the leaves of Ocimum gratissimum, Vernonia amygdalina and Moringa Oleifera plants found within our vicinity in Nigeria. The analyses were investigated in accordance with standard procedures and compared. Of the 3 plants, M. oleifera had highest (P<0.05) crude fat, crude protein and total ash but lowest...

Author(s): M. D. Olumide, O. A. Ajayi and O. E. Akinboye