February 2007
Central nervous system stimulant effect of the ethanolic extract of Kigelia africana
CNS stimulant effect of the ethanolic stem bark extract of Kigelia africana was studied in mice using the barbiturate induced sleeping time and the Rota rod bar to check the extract’s effect on muscle coordination. The results showed that the extract at all doses tested reduced the duration of sleeping time when compared to the control group that received distilled water. This difference in sleeping time...
February 2007
Anti-inflammatory bio-activities in water extract of Centaurea ainetensis
Of a selected 29 plants endemic to Lebanon and claimed to have anti-inflammatory effects, according to Lebanese folk literature, Centaurea ainetensiswas chosen to further characterize its claimed anti-inflammatory activity using in-vitro and in-vivo assays. Water extract from C. ainetensis, at non-cytotoxic concentrations, inhibited in a dose dependant manner interleukin-6 (IL-6) and gelatinases A...
February 2007
The beneficial effects of garlic oil and garlic cake on coconut oil fed rats
The feeding of coconut oil (CNO) at a level of 20% in terms of energy to normal rats for a month increased significantly blood sugar and lipids and protein content and lipid peroxidation in tissues (viz. Heart, liver and kidney) and enhanced the activities of aspartate and alanine aminotransferases and alkaline phosphatase in serum. Oral administration of garlic oil (100 mg/kg body wt) or cake (5%...
February 2007
Preliminary studies on anti-inflammatory and analgesic activities of Securinega virosa (Euphorbiaceae) in experimental animal models
Securinega virosa is a commonly used medicinal plant in West Africa sub-region for the management of painful and inflammatory conditions. In the present study, the analgesic and anti-inflammatory activities of methanol root bark extract of S. virosa (SV) were investigated. The anti-inflammatory activity was evaluated using carrageenan-induced rat paw oedema while analgesic activity was tested by acetic...
February 2007
Clonal propagation and antimicrobial activity of an endemic medicinal plant Stevia rebaudiana
A procedure has been outlined for plant regeneration and antimicrobial screening of a medicinal herb, Stevia rebaudiana Bertoni, through in vitro culture of nodal segments with axillary buds. Murashige and Skoog (MS) medium supplemented with 2.0 mg/L N6-benzyl amino purine and 1.13 mg/L indole-3-acetic acid in combination were found to be most effective in inducing bud break and growth, and in initiating...
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