Journal of
Physiology and Pathophysiology

  • Abbreviation: J. Physiol. Pathophysiol.
  • Language: English
  • ISSN: 2141-260X
  • DOI: 10.5897/JPAP
  • Start Year: 2010
  • Published Articles: 45

Full Length Research Paper

Evaluation of ventilatory function of Senegalese patients with type 2 diabetes

Arame Mbengue
  • Arame Mbengue
  • Laboratory of Physiology, UFR of Health Sciences of Thies, Service Functional Explorations of the Regional Hospital of Thies, Senegal.
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Mor Diaw
  • Mor Diaw
  • Laboratory of Physiology and Functional Explorations, FMPO/UCAD, Dakar, Senegal.
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Mame Saloum Coly
  • Mame Saloum Coly
  • Laboratory of Physiology, UFR of Health Sciences of Thies, Service Functional Explorations of the Regional Hospital of Thies, Senegal.
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Abdou Khadir Sow
  • Abdou Khadir Sow
  • Laboratory of Physiology and Functional Explorations, FMPO/UCAD, Dakar, Senegal.
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Salimata Houndjo Faye
  • Salimata Houndjo Faye
  • Laboratory of Physiology and Functional Explorations, FMPO/UCAD, Dakar, Senegal.
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Fatoumata Ba
  • Fatoumata Ba
  • Laboratory of Physiology, UFR of Health Sciences, Gaston Berger University of Saint- Louis, Saint-Louis, Senegal.
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Fatou Bintou SAR
  • Fatou Bintou SAR
  • Laboratory of Physiology, UFR of Health Sciences of Thies, Service Functional Explorations of the Regional Hospital of Thies, Senegal.
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Abdoulaye Ba
  • Abdoulaye Ba
  • Laboratory of Physiology and Functional Explorations, FMPO/UCAD, Dakar, Senegal.
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  •  Received: 18 September 2019
  •  Accepted: 28 October 2019
  •  Published: 30 November 2019

Abstract

Diabetes is a common disease in sub-Saharan Africa. Complications associated with type 2 diabetes mellitus are due to macro-vascular and micro-vascular lesions. One of the less known complications of diabetes is impaired respiratory function. The objective of this study was to evaluate the ventilatory function of Senegalese type 2 diabetics. A total of Sixty-four women composed to 32 diabetic subjects and 32 healthy control individuals were included in this study. Spirographic recording was realized for the two groups. The HbAc1of diabetic patients was measured and duration of diabetic status was estimated and the diabetic groups were sub-divided according to HbA1C level (group -a>7.5%, group- b ≤ to 7.5%) and diabetic duration (group a> to 10 years and group< to 10 years). It was observed that 59% of diabetic patients had an obstructive bronchial which was localized in the distal bronchi. For the restrictive syndrome it was found in 31% of population with diabetic. Diabetes could cause a restrictive and obstructive ventilatory disorder. This phenomonea might probably be due to glycosylation abnormalities linked to type 2 diabetes.

Key words: Type 2 diabetes, spirometry, obstructive ventilatory disorder, restrictive ventilatory disorder.