Journal of
Public Health and Epidemiology

  • Abbreviation: J. Public Health Epidemiol.
  • Language: English
  • ISSN: 2141-2316
  • DOI: 10.5897/JPHE
  • Start Year: 2009
  • Published Articles: 584

Full Length Research Paper

Plasmodial infection and haematological parameters in febrile patients in a hospital in Oyo town, South-western Nigeria

Adedotun A. A., Salawu O. T., Morenikeji, O. A.* and Odaibo A. B.
Parasitology Research Unit, Department of Zoology, University of Ibadan, Oyo, Nigeria
Email: [email protected]

  •  Accepted: 05 October 2012
  •  Published: 31 March 2013

Abstract

A cross-sectional study on Plasmodium infection was conducted among 158 febrile patients (65 males and 93 females) reporting to Oyo State Hospital, Oyo, South-western Nigeria. Parasitological and haematological examinations of the blood samples were conducted. An overall infection rate of 29.7% was observed with parasite densities ranging from 96 - 64680 asexual parasites/µL blood. The percentages of infected male and female individuals were 27.7 and 31.2%, respectively. The least (12.5%) and the highest prevalence (44.4%) were recorded in age groups <1 and 6 - 15 years respectively. Malaria prevalence and parasitaemia were independent of age and sex (P>0.05). The total leucocytes and lymphocytes decreased with parasites densities, while neutrophils increased with parasitaemia but with insignificant relationships (P>0.05). The neutrophils and lymphocytes in infected and non-infected individuals were (54.0, 55.6%) and (45.9, 43.73%) respectively. The mean packed cell volume (PCV) of the blood in all positive cases in all age groups was lower than in negative individuals. The malaria prevalence in this study was low. Therefore, considerable efforts should further be made to reduce its occurrence below the risk level mostly among the most susceptible groups. Advocacies on the practices of Intermittent Preventive Treatment (IPT) and use of Insecticide Treated Nets (ITNs) should further be promoted.

 

Key words: Plasmodium infection, parasitaemia, prevalence, haematology, Oyo town.