Journal of
Public Health and Epidemiology

  • Abbreviation: J. Public Health Epidemiol.
  • Language: English
  • ISSN: 2141-2316
  • DOI: 10.5897/JPHE
  • Start Year: 2009
  • Published Articles: 513

Full Length Research Paper

Relationship between plasma levels of albumin, selenium, chromium and manganese of healthy subjects and patients with human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS), diabetes mellitus and cardiovascular disease in Akwa-Ibom and Cross River States of Nigeria

Kolawole Sunday E.*
  • Kolawole Sunday E.*
  • National Open University of Nigeria, Benin Study Centre, Benin City, Edo State, Nigeria.
  • Google Scholar
Obueh Henrietta O
  • Obueh Henrietta O
  • Biology Department, College of Education, Ekiadolor, Benin City, Edo State, Nigeria.
  • Google Scholar


  •  Received: 08 September 2014
  •  Accepted: 15 April 2015
  •  Published: 31 May 2015

Abstract

Plasma albumin, selenium, chromium and manganese levels of thirty patients each with HIV/AIDS, diabetes mellitus and cardiovascular disease (CVD), and one hundred and six apparently healthy adults in Akwa-Ibom and Cross River States, South-South Nigeria was studied. The mean plasma albumin was higher in the control than in the disease patients. The mean plasma selenium was lowest in the control (0.004 ± 0.01 mg/L) than in the HIV/AIDS (0.007 ± 0.00 mg/L), diabetes mellitus (0.007 ± 0.00 mg/L) and CVD (0.010 ± 0.00 mg/L) patients. The mean plasma chromium was highest in the HIV/AIDS patients (0.125 ± 0.45 mg/L) and lowest in the diabetes mellitus patients (0.106 ± 0.04 mg/L). Plasma manganese level was highest in the control (0.028 ± 0.02 mg/L). Manganese was detected in the plasma of all the diseased patients. For the total healthy subjects, only 55.67, 68.87 and 83.93% had selenium, chromium and manganese detected in their blood plasma. There was no significant correlation between plasma levels of albumin, selenium, chromium and manganese (P > 0.05) in the control. The poor nutritional status of the disease patients was reflected by the depressed albumin levels.

 

Key words: Health, disease, trace elements, plasma levels.