The discovery of TB cases in 2016 was 658 and the number of patients treated was 470 patients and Puskesmas Semanding became the health center with the largest number of patients reaching 40 patients with the number treated 35 patients. Which means it has not reached 100% of patients treated, and found 2 of them experienced resistance or including the MDR-TB group. OAT resistance is due to patients not adhering to the rules of taking medication. One of them is caused by motivation deficit. The purpose of this study was to analyze the effect of motivation on the accuracy of OAT consumption in TB patients. This research is a pre-experimental design. The population is TB patients at the Semanding Health Center, Tuban. The sampling technique was purposive sampling probability with a total of 30 TB patients, taken according to inclusion criteria. The independent variable is the provision of motivational therapy. The dependent variable is OAT consumption compliance. Instrument for observation sheets and questionnaires. Data analysis using Chi Square test with a significance level of 0.05. The study showed adherence to taking medication after therapy was less than 2 people before therapy or 6.67%, after therapy was greater than 19 before or 63.33% of people before therapy, adherence after therapy was equal to as much pre-treatment adherence 9 people or 30%. This study shows that the majority of respondents showed positive differences in changes in adherence to medication after being given motivational therapy by researchers. Motivation has a significant influence in increasing the compliance of TB patients in undergoing OAT therapy with a significance value of Chi Square test = 0.00. Based on the results of this study, it is expected that the Puskesmas will be able to provide policies and attention to the importance of providing motivation in the form of health education and counseling and the provision of PMO (supervision of taking medication) or supervision in order to succeed in controlling and eradicating TB cases.

Keywords: Pulmonary Tuberculosis, Motivation, Drug Adherence