December 2011

Pharmacology and phytochemistry of Coccinia indica

Coccinia indica (Bimba, kanduri, Cucurbitaceae) is famous for its hypoglycemic and antidiabetic properties in Ayurvedic system of medicine. Other applications include the therapy of various conditions such as skin diseases and gonorrhoea. The present review highlights the phytochemistry and pharmacology of Coccinia indica. There are many patented formulations derived from C. indica which are now...

Author(s): U. A. Deokate and S. S. Khadabadi

December 2011

4-(ethyl-p-chlorophenylglycinylamino)-7-chloroquinoline: Synthesis and in vivo antimalaria evaluation

4-amino-7-chloroquinoline derivative was synthesized and characterized using both1D and 2D nuclear magnetic resonance (NMR) techniques, with the application of correlation spectroscopy (COSY), nuclear overhauser enhancement spectroscopy (NOESY), heteronuclear multiple bond correlation (HMBC), heteronuclear single quantum coherence (HSQC), liquid chromatography-mass spectroscopy (LC-MS) and infra-red (IR)...

Author(s): Habila J. D., Habila N., Ndukwe I. G., Amupitan J. O., Nok A. J. and Shode F. O.