Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009

JPP Articles in press

Article in Press

Tea tree oil a new natural adjuvant for inhibiting glioblastoma growth

Tea Tree oil (TTO), the essential oil from the Australian native Melaleuca alternifolia has demonstrated a variety of beneficial efficacies including antimicrobial, antifungal, antiviral and anti-inflammatory. This report discusses data obtained on the in vitro activity of TTO on human glioblastoma cells U87MG. Cell viability was examined by 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazolium bromide MTT assay. Growth...

Author(s):Antonietta Arcella, Maria Antonietta Oliva, Sabrina Staffieri, Massimo Sanchez, Michele Madonna, Salvatore Castaldo , Felice Giangaspero and Luigi Frati

Article in Press

Pharmacognostic, physicochemical and phytochemical evaluation of the leaves of Fadogia cienkowskii Schweinf (Rubiaceae)

Fadogia cienkowskii is a shrub used in folklore medicine. Evaluations of the leaves were carried out to determine the macroscopic, microscopic, chemomicroscopic, physicochemical and phytochemical profiles using standard methods. The macroscopic examination revealed fresh leaves are green, ordourless with a bitter taste. The leaf is oblong-elliptic in shape and sub-acute at apex; rounded at the base with entire margin....

Author(s):Bruce S.O, Onyegbule F.A. and Ezugwu C.O

Article in Press

Hepatoprotective potential of Blepharis persica (burm. f.) o. kuntze.

This study aimed to assess the hepatoprotective activity of ethanol (90%) extract of Blepharis persica seeds (BPEE) in rats. The plant extract showed a remarkable hepatoprotective activity against acetaminophen-induced hepatotoxicity as judged from the serum marker enzymes and histopathological studies on liver tissues. The acetaminophen-induced group shows a significant rise in the serum enzymes. Treatment of rats with...

Author(s):Vichitra Kaushik, Gagandeep Chaudhary, Shoaib Ahmad, Vipin Saini, A. Pandurangan, Manish Kumar and G. Arunachalam

Article in Press

Characterization of the chemical composition of Lippia alba Mill. essential oil in the dry and rainy seasons

Lippia alba is a native species popularly known as "lemon balm", used in folk medicine for the treatment of several diseases. This work aims to study the ethnobotany of L. alba and to determine the chemical composition of essential oils from the fresh leaves of L. alba during both rainy and dry seasons. The volatile contents of the oil samples were determined by Gas Chromatography coupled to Mass Spectrometry - GC/MS. The...

Author(s):Rodrigo Dias Alves, Ianara Mendonça da Costa, Francisca Overlânia Vieira lima, Luciana Cristina Borges Fernandes, Dinalva Brito de Queiroz, Eduardo Pereira de Azevedoc, Jacqueline do Carmo Barreto and Fausto Pierdoná Guzen

Article in Press

Medicinal Value of the Seed Essential Oil of Eucalyptus citriodora Hook

Eucalyptus essential oil is an important aroma-therapeutic agent in the treatment of diverse diseases and ailments in human and animals. The aim of this study was to determine the composition and pharmacological properties of the seed essential oil of E. citriodora from Nigeria. The essential oil was extracted by hydro-distillation using Clevenger-type apparatus and analyzed using GC-MS. The total phenolic content,...

Author(s):Ololade, Z.S. and Olawore, N.O.

Article in Press

Acute and subchronic toxicity assessment of Melastomastrum capitatum Fern. leaf methanol extract in Wistar albino rats

This study was carried in order to determine short-term (acute) and long-term(subchronic) effects of Melastomastrum capitatum leaf methanol extract in the management and treatment of certain diseases in traditional and complementary medicines by many villages in Mambila Nigeria. Acute and subchronic toxicities were carried out in accordance with the Organization for Economic Cooperation and Development (OECD) guidelines....

Author(s):Cletus Anes Ukwubile, Abubakar Ahmed, Umar Adamu Katsayal, Jamilu Ya'u and Henry I. Nettey

Article in Press


The roots of Chasmanthera dependens were studied to determine their active constituents and antimicrobial activity. A phytochemical investigation of C. dependens using chloroform and methanol extracts led to the isolation and identification of the following secondary metabolites; alkaloids, flavonoids, tannins, phenolics, carbohydrates, reducing sugars, terpenoids, steroids, saponins. The antimicrobial activities of these...

Author(s):Anosike, Chioma Assumpta., Nwachukwu, Justus Nmaduka, Ogbozor, Chinedu. Samuel and Madueke, Chidi Augustine.

Article in Press


Objective: To study detailed Pharmacognostic profile and preliminary phytochemical investigation of the leaves of Indigofera tinctoria Linn. commonly known as ‘indigo’ belongs to the family Fabaceae. It is distributed through the hotter parts of India. Medicinal uses include the juice of the leaves as a prophylactic against hydrophobia, and as a decoction for blennorrhagia; plant extract as the treatment for epilepsy,...

Author(s):Dhanapal Venkatachalam

Article in Press


Objectives: This study covers the microscopic studies, the phytochemical screening, acute toxicity evaluation and anti-inflammatory activity of the methanol extract of the leaves of Sabiceabrevipes. This plant has not been studied extensively; even when such studies were done; the focus was on the root rather than the leaf, which is easier to harvest and more abundant. Method: Free hand sections were used for anatomical...

Author(s):Michel Kenne Tchimene, Sunday Patrick Gaza Anze, Christopher Obodike Ezugwu and Maurice Mmaduakolam Iwu

Article in Press

Comparative Proximate Composition and Hypoglycemic Properties of Three Medicinal Plants (Verononiaamygdalina, AzadirachtaindicaandMoringaoleifera).

The present study sought to investigate proximate composition in relation to the short and long term hypoglycemic effects of ethanol/water extracts of Verononiaamygdalina, AzadirachtaindicaandMoringaoleifera on hyperglycemic rats. Hyperglycemia was induced by single intra-peritoneal injection of 0.1 mol/L alloxan monohydrate in citrate buffer (pH = 4.5); dosage = 140 mg/kg; b/w.Hyperglycemic rats received separate dose of...

Author(s):Chikezie P.C and Ojiko O.A

Article in Press

Anti-inflammatory and antioxidant activity of Ixora coccinea stems

Background and objective: Ixora coccinea has mentioned in Ayurveda as Paranti and traditionally stems used in inflammatory diseases like sprains, eczema, contusions and boils. Present study deals with assessment of anti-inflammatory and antioxidant activity of extracts of I. coccinea stem. Methodology: Anti-inflammatory activity was accessed by in vivo carrageenan-induced paw edema in rat and in vitro human red blood...

Author(s):Ajaykumar Rikhabchand Surana and Rajendra Dayaram Wagh

Article in Press


Tea and coffee have been consumed for hundreds of years for their flavour and stimulating properties. Nowadays, caffeine is receiving an increasing interest in food and pharmaceutical industries due to its central nervous system CNS stimulating properties, peripheral vasoconstriction, relaxation of the smooth muscle and myocardial stimulation. Caffeine constitutes an average of 4% of tea leaf and 1.5% of coffee bean. The...

Author(s):Hattem Mohamed Mekky

Article in Press


Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, plants provide a potential source of hypoglycemic...

Author(s):Maninder Kaur

Article in Press

GC-MS Phytochemical Profiling and Anti-hypercholesterolemia Potentials of Cnidoscolus aconitifolius Leaf Extracts in Male Albino Rats.

The present study investigated phytochemical constituents of Cnidoscolus aconitifolius leaves extracts and its anti-hypercholesterolemia potentials using standard analytical methods. Forty five male albino rats weighing (115-121g) were used for the study. The rats were randomly divided into nine groups of five rats each. Group I served as the control while the other groups were administered 200, 400, 600 and 800mg/kg body...

Author(s):Uhegbu F.O., Chukwu E.C and Osuocha K.U

Article in Press

Fungal metagenomes in polyherbal medicines used for the treatment of tuberculosis

The traditional systems of medicine have significantly become more accepted in the developed and developing countries due to their curative property, less toxicity and minimal side effects. However, several studies have shown that they are associated with microbial contaminants. This study aimed at identifying fungi in nine polyherbal medicines used for the treatment of tuberculosis in Eastern Cape Province, South Africa....

Author(s):Elizabeth Bosede Famewo, Anna Maria Clarke and Anthony Jide Afolayan

Article in Press

Antimicrobial activity of leaf and flower extracts of Ocimum gratissimum on selected microorganisms

The antimicrobial activities of flower and leaf extract of Ocimum gratissimum obtained from the garden of the Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology Ghana, was tested against Staphylococcus aureus, Bacillus subtilis (Gram positive bacteria), Klebsiella pneumonia, Pseudomonas aeruginosa, Escherichia coli (Gram negative bacteria) and Candida albicans (fungi). These...

Author(s):Aryee Feizel Ayitey

Article in Press

Development of Validated High performance thin layer chromatography method for simultaneous determination of quercetin and kaempferol in Thespesia populnea

Thespesia populnea L. (Family: Malvaceae) is a well-known medicinal plant distributed in tropical regions of world and cultivated in south Gujarat and indicated to be useful in cutaneous affections, psoriasis, ringworm and eczema. Bark and fruits are indicated in the diseases of skin, urethritis and gonorrhea. The juice of fruits is employed in treating certain hepatic diseases. The plant is reported to contain flavanoids,...

Author(s):Hiteksha Panchal, Aeshna Amin and Mamta Shah

Article in Press

Potential of Kelakai plants (Stenochlaena palustris (Burm.F.) Bedd.) from Central Kalimantan as aphrodisiac

The necessity for traditional medicine is efficacious as aphrodisiac increases every year. Dayak community believes that Kelakai roots have efficacy as an aphrodisiac drug, but no studies were conducted relating to the efficacy of the Kelakai roots.Traditional medicinal products are efficacious as aphrodisiac have a hormone-like effect, usually contain active ingredients that have estrogenic properties among other things...

Author(s):Fahruni, Rezqi Handayani and Susi Novaryatiin

Article in Press


Garcinia hanburyi belongs to the family Clusiaceae. The whole plant was dried, extracted to obtain Xanthone rich extract. Phytochemical studies of extract showed the presence of Phenols, Alkaloids, steroids, resins and saponins. The natural sources such as a plants are an abundant source having various medicinal properties. In the present study, Garcinia hanburyi has been selected to test for the Anti-inflammatory activity...

Author(s):J. Narayanan and V.CHITRA

Article in Press

Biochemical and antibacterial activity of Jojoba Oil ‘Simmondsia chinensis’ in rats

This study has evaluated the antibacterial effect of Jojoba oil (J.O) in vivo against Staphylococcus aureus. One hundred mature male Sprague Dawley rats were divided into four groups, including the control groups and the groups treated with J.O. as part of the diet mixture (2.5% of total body weight). Our findings suggest a significant increase in body weight gain (94.0 ±5.404 g for J.O treated rats in comparison to 72.0...

Author(s):Shahd Abuhelal

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