Journal of
Parasitology and Vector Biology

  • Abbreviation: J. Parasitol. Vector Biol.
  • Language: English
  • ISSN: 2141-2510
  • DOI: 10.5897/JPVB
  • Start Year: 2009
  • Published Articles: 189

Full Length Research Paper

Coverage and effectiveness of intermittent preventive treatment of malaria with Sulfadoxine-Pyrimethamine during pregnancy in six sentinels’ sites of Côte d’Ivoire

Offianan Andre TOURE
  • Offianan Andre TOURE
  • Maludology Unit, Institut Pasteur de Côte d'Ivoire.
  • Google Scholar
Serge-Brice ASSI
  • Serge-Brice ASSI
  • Institut Pierre Richet / National Malaria Control Program Côte d'Ivoire.
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Valerie Akoua BEDIA
  • Valerie Akoua BEDIA
  • Department of Parasitology Mycology UFR Pharmaceutical and Biological Sciences, University Felix Houphouet Boigny, Côte d'Ivoire.
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Landry Tiacoh N’GUESSAN
  • Landry Tiacoh N’GUESSAN
  • Maludology Unit, Institut Pasteur de Côte d'Ivoire.
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Thomas Yapo ABA
  • Thomas Yapo ABA
  • Infectious Diseases Services UFR Medical Sciences, Allassane Ouattara University, Côte d'Ivoire.
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Kalou Dibert ZIKA
  • Kalou Dibert ZIKA
  • Department of Parasitology Mycology UFR Medical Sciences, Allassane Ouattara University, Côte d'Ivoire.
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Abibatou KONATE
  • Abibatou KONATE
  • Department of Parasitology Mycology UFR Pharmaceutical and Biological Sciences, University Felix Houphouet Boigny, Côte d'Ivoire.
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Pulcherie Marie Christiane KIKI-BARRO
  • Pulcherie Marie Christiane KIKI-BARRO
  • Department of Parasitology Mycology UFR Pharmaceutical and Biological Sciences, University Felix Houphouet Boigny, Côte d'Ivoire.
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William YAVO
  • William YAVO
  • Department of Parasitology Mycology UFR Pharmaceutical and Biological Sciences, University Felix Houphouet Boigny, Côte d'Ivoire.
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Koffi Daho ADOUBRYN
  • Koffi Daho ADOUBRYN
  • Department of Parasitology Mycology UFR Medical Sciences, Allassane Ouattara University, Côte d'Ivoire.
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Eby Ignace Hervé MENAN
  • Eby Ignace Hervé MENAN
  • Department of Parasitology Mycology UFR Pharmaceutical and Biological Sciences, University Felix Houphouet Boigny, Côte d'Ivoire.
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Emmanuel BISSAGNENE
  • Emmanuel BISSAGNENE
  • GSA National Malaria Control Program, Côte d'Ivoire.
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  •  Received: 31 May 2021
  •  Accepted: 29 July 2021
  •  Published: 30 September 2021

Abstract

Intermittent preventive treatment of malaria during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) is recommended to prevent maternal and neonatal adverse outcomes. This study aimed to assess IPTp-SP coverage in mothers delivering in six health facilities and factors associated with placental malaria and low birth weight. A multicenter, cross-sectional survey was conducted in Côte d’Ivoire from March to October 2017. Regression logistics were used to study factors associated with placental malaria, IPTp-SP uptake, and LBW (<2.500 grams). Out of all the enrolled participants (n=1236), 632 (51.1) received three or more doses of SP while 288 (23.3%), 221 (17.9%) and 95 (7.7%) received two respectively, one and none dose of SP. Uptake of ≥ 3 doses varied significantly (p < 0.001) according to study site, number of ANC visits and profession. Regression analysis identified primigravidae, single dose IPTp-SP, or no IPTp-Sp as factors associated with placental malaria.  IPTp-SP coverage observed in this study was low compared to WHO recommendation and contrasted with the high antenatal care (ANC) visits. There is a need for further research to understand the barriers and enablers of uptake in each context in order to improve uptake of adequate IPTp-SP regimen.

Key words: Coverage, Effectiveness, Malaria, Pregnancy, IPTp-SP, Côte d’Ivoire.