Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009
  • Published Articles: 197

Table of Content: October 2014; 6(8)

October 2014

Determination of the effects of some artificial sweeteners on human peripheral lymphocytes using the comet assay

In this study, the genotoxicity of the artificial sweeteners acesulfame potassium, aspartame, saccharin, and sorbitol, which are used in food industry and by patients with diabetes, was investigated in human peripheral lymphocyte cells using the single-cell gel electrophoresis (comet) technique. Human lymphocyte cells were treated with the substances for three hour at each of the three dosages (1.25, 2.5, and 5 ppm)....

Author(s): Zeynep Fındıklı and Şifa Türkoğlu

October 2014

Bioaccumulation of heavy metals in cane rat (Thryonomys swinderianus) in Ogun State, Nigeria

Wild animals have provided complimentary protein for human populations across the world over the centuries. This study investigated on bioaccumulation of heavy metals in different organs of cane rat (Thryonomys swinderianus) and the health implications of its consumption. Four carcasses were collected from each of the four ecotomes (Mosinmi, Agbara, Omo forest reserve and Ibese) and concentrations of 7 heavy metals (Fe,...

Author(s): Durojaye A. Soewu, Olufemi M. Agbolade, Rasheed Y. Oladunjoye and Ibukun A. Ayodele

October 2014

Effect of dipentyl phthalate in 3-dimensional in vitro testis co-culture is attenuated by cyclooxygenase-2 inhibition

Exposure to phthalate esters is associated with changes in steroidogenesis, leading to the hypothesis that this is a primary mechanism of phthalate reproductive toxicity. However, some phthalate-induced male reproductive toxicity has been demonstrated in the absence of changes to testosterone production, suggesting additional mechanisms of action. There is evidence that phthalate exposure increases expression of the...

Author(s): Susanna Wegner, Xiaozhong Yu, Hee Yeon Kim, Sean Harris, William C. Griffith, Sungwoo Hong and Elaine M. Faustman