Mastitis is a multi-etiological, complicated disease characterized by an inflamed mammary gland parenchyma caused by microbes, most commonly by bacteria those infiltrate the udder, proliferate, and produce toxins that harm the mammary gland. A cross-sectional study on lactating cattle was undertaken from December 2019 to July 2020 to investigate the prevalence and potential risk factors of bovine mastitis in and around Jigjiga. At the individual level, the total prevalence of mastitis was determined to be 27.2%. Clinical and subclinical mastitis were found in 4.8 and 22.4% of individual cows, respectively. It was also demonstrated that there was an association between mastitis and bovine breeds (OR?=?0.13, CI?=?0.05-0.32), different age groups (OR?=?0.27, CI?=?09-0.77), lactation stages (OR?=?4.40, CI?=?1.64-11.8), parities (OR?=?0.15, CI?=?0.05-0.42), history of previous mastitis (OR?=?10.13, CI?=?4.11-24.9), and husbandry (OR?=?0.06, CI?=?0.02-0.20), which all had statistically significant (P<0.05) impact on the current prevalence of bovine mastitis in the study area. As the results show a higher prevalence of mastitis and a significant association between the risk factors and the mastitis in the study area, immediate control measures are required.

Keywords: Bovine, Mastitis, Prevalence, Public Health, Risk Factors